摘要
目的探讨功能性构音障碍(FAD)患儿中枢听觉加工特点及儿童FAD的可能病因。方法选择符合FAD诊断标准的27例患儿作为病例组,年龄匹配的正常儿童50例作为对照组,比较病例组与对照组个人语言发育史阳性病史率,检测二组儿童事件相关电位,比较其失匹配负波(MMN)形态学、潜伏期及峰振幅。结果病例组个人语言发育史中阳性病史比例显著高于对照组,差异有统计学意义(70%vs 8%,P<0.01);其MMN峰潜伏期较对照组显著延长,差异有统计学意义(209±31 ms 175±32 ms,P<0.01);其峰振幅低于对照组,但差异无统计学意义(P>0.05)。结论中枢听觉加工时间延长可能是儿童FAD的发病原因之一。
Objective To investigate the central auditory processing function in children with functional articulation disorders （FAD）, and ssible causes of FAD. Methods Twenty-seven children with FAD were selected as the case group and 50 age-matched normal children were selected as the control group. The two groups were compared with respect to the following factors： percentage of individuals with a positive history of language development disorder, and the form, peak latency and peak amplitude of mismatch negativity （MMN） on auditory event-related potentials. Results Compared with the control group, the case group had a significantly higher percentage of individuals with a positive history of language development disorder （70% vs 8%; P〈0.01）, a significantly prolonged peak latency of MMN （209±31 ms vs 175±32 ms; P〈0.01）, and an insignificantly lower peak amplitude of MMN （P〉0.05）. Conclusions Prolonged central auditory processing may be one of the causes ofFAl） in children.
出处
《中国当代儿科杂志》
CAS
CSCD
北大核心
2013年第8期653-656,共4页
Chinese Journal of Contemporary Pediatrics
关键词
失匹配负波
功能性构音障碍
事件相关电位
中枢听觉加工
儿童
Mismatch negativity
Functional articulation disorder
Event-related potential
Central auditoryprocessing
Child
作者简介
高延，女，硕士，副主任医师。
主任医师。
