摘要
目的应用前节光学相干断层扫描仪（OCT），比较waveLightFS200飞秒激光与MoriaM290角膜板层切开刀制作角膜瓣的厚度及形态特点。方法前瞻性病例对照研究。对61例行双眼准分子激光原位角膜磨镶术（LASIK）的近视患者分别采用WaveLightFS200飞秒激光制瓣（WaveLight组，36例）和MoriaM290角膜板层切开刀制瓣（Moria组，25例）。术后1周，采用Visante前节OCT测量180°、90°、45°、135。轴位上距离角膜顶点0、±2、±3．5mm处的角膜瓣厚度。运用独立样本t检验对2组数据进行统计学分析。结果WaveLight组中央角膜瓣厚度为（105．53±5．86）μm，而Moria组为（132．96±13．91）μm（t=-13．16，P〈0．01）。WaveLight组中央角膜瓣精确度为（6．17±3．98）μm，而Moria组为（23．60±2．64）μm（t=-15．20，P〈0．01）。WaveLight组角膜瓣均匀性指数为（4．07_＋0．94）μm，Moria组为（8．48±2．35）μm（t=12．60，P〈0．01）。WaveLight组角膜瓣的对称性指数[（33．81±11．28）μm]明显小于Moria组[（68．46±26．66）μm]，差异有统计学意义（t=8．67，P〈0．01）。结论前节OCT显示WaveLightFS200飞秒激光制作的角膜瓣与MoriaM290角膜板层切开刀相比，中央厚度更精确、重复性更好，角膜瓣形态更均匀。
Objective To evaluate and compare the thickness and morphology of laser in situ keratomileusis （LASIK） flaps created by either the WaveLight FS-200 femtosecond laser or the Moria microkeratome M2 90 using anterior segment optical coherence tomography （AS-OCT）. Methods This was a prospective case-control study. Bilateral LASIK was performed on 61 myopic patients. Flaps were created using the WaveLight FS-200 femtosecond laser in 72 eyes and the Moria M2 90 microkeratome in 50 eyes. The thickness at 17 points across each flap, 0 mm, ＋2 mm, and ＋3.5 mm to the corneal vertex on the horizontal, vertical, 45°and 135° meridians, were evaluated using a Visante AS-OCT at 1 week postoperatively. An independent t test was used. Results The central flap thickness of the WaveLight group was 105.53±5.86μm, while it was 132.96±13.91 μm in the Moria group （t=-13,16, P〈0.01）. The difference between the achieved and the intended flap thickness （accuracy） was 6.17±3.98 μm and 23.60±12.64μm, respectively （t=-15.20, P〈0.01）. The standard deviation of thickness in the 17 points within an individual flap （uniformity） was 4.07±0.94 μm in the WaveLight group and 8.48±2.35 μm in the Moria group （t=-12.60, P〈0.01）. The index S （Symmetry） of Moria group （33.81±11.28μm） was significantly smaller in the WaveLight group （68.46±26.66μm） （t=-8.67, P〈0.01）. Conclusion AS-OCT showed that the flaps created with the WaveLight FS-200 femtosecond laser were more accurate, reproducible, and uniform than those created with the Moria M2 90 microkeratome.
出处
《中华眼视光学与视觉科学杂志》
CAS
2013年第7期401-404,共4页
Chinese Journal Of Optometry Ophthalmology And Visual Science
关键词
飞秒激光
角膜瓣
角膜磨镶术
激光原位
体层摄影术
光学相干
前节
Femtosecond laser
Corneal flap
Keratomileusis,laser in situ
Tomography, optical coherence, anterior segment
作者简介
通信作者：陈跃国，Email：chenyueguo@263．net
