摘要
目的:研究和评价甘利欣治疗慢性乙肝的疗效和护理。方法:选择慢性乙肝患者48例,分为甘利欣治疗组28例和对照组20例,治疗组在对照组基础上加用甘利欣30～60ml,加入5%葡萄糖500ml中静脉滴注,1次/d。结果:两组患者治疗后肝功能较治疗前均有明显的改善,ALT和AST含量均有显著降低,A/G比值均有所提高,且甘利欣治疗组治疗后明显优于对照组(P<0.05)。甘利欣治疗组HBeAg阴转率、抗HBe阳转率均明显优于对照组(P<0.05),但两组HBsAg阴转率比较差异无统计学意义(P>0.05)。结论:甘利欣可有效地降低ALT与AST,提高A/G比值,防止正常肝细胞损害,保护肝功能,减少出血、肝肾综合征、肝性脑病等并发症,从而降低病死率,提高存活率。甘利欣是治疗慢性乙肝的有效药物。
Objective：To research and evaluation Ganlixin method and efficacy for the treatment of chronic hepatitis.Method：Collecting 48 cases of patients with chronic hepatitis B.Among them,28 cases patients of Ganlixin treatment group and 20 cases patients of the control group.Using Ganlixin 30-60 ml,added 5% glucose 500 ml intravenous drip once a day. Result：Two groups of patients after treatment than before treatment had A significant improvement in the liver function,ALT and AST levels were significantly reduced,improved A/G ratio and GanLiXin treatment group was better than control group after treatment（ P〈0.05）.GanLiXin treatment group rate of HBeAg Yin turn,HBe Yang turn rate were significantly better than control group（ P〈0.05）,but the HBsAg negative transfer rate is similar between the two groups has no statistical significance（ P〈0.05）.Conclusion： Ganlixin to be effective in reducing ALT and AST,improve the A/G ratio,To prevent normal liver cell damage,protection of liver function,reduce the complications of bleeding,hepatorenal syndrome,hepatic encephalopathy,and thereby reduce mortality,improve survival.Ganlixin is an effective drug for the treatment of chronic hepatitis B.
出处
《中国医学创新》
CAS
2013年第20期135-136,共2页
Medical Innovation of China
关键词
甘利欣
慢性乙肝
疗效
Ganlixin
Hepatitis B
Efficacy
作者简介
通讯作者：张会荣
