摘要
目的分析术中直肠冲洗对直肠癌前切除术患者预后的影响。方法分析2006年5月至2007年11月中国医学科学院肿瘤医院腹部外科手术的144例直肠癌根治性前切除术患者的临床资料。将144例分为两组，术中直肠冲洗组69例，同期未冲洗组75例，比较两组患者的术后局部复发率及术后5年无瘤生存率。应用SPSS13．0进行统计学分析，计数资料比较采用X2检验，计量资料采用t检验，Kaplan—Meier法计算术后生存率。结果直肠冲洗组有55例在冲洗液中找到脱落癌细胞，阳性率达79．7％；直肠冲洗组术后局部复发率为4．6％，未冲洗组为6．7％（x2=0．368，P=0．721）；两组患者术后5年无瘤生存率分别为79．7％和74．7％（X2=0．517，P=0．553）。结论直肠癌前切除术中，直肠腔内脱落癌细胞的阳性率高，直肠冲洗能够有效清除脱落的癌细胞，可能降低局部复发率并提高远期生存率。
Objective To evaluate the influence of rectal washout on the prognosis of rectal cancer after anterior resection. Methods Data of 144 patients with rectal cancer undergoing anterior resection at Chinese Academy of Medical Science Cancer Hospital between May 2006 and November 2007 were reviewed. 69 patients received rectal washout and 75 patients did not. The incidences of recurrence and 5-year disease-free survival rates were compared. Data were analyzed by SPSS 13.0 software packet, using X2 and t inspection. Kaplan-Meier method was used to calculate postoperative survival rate. Results Washing sample was positive for malignant cells in 55 patients （79. 7% ）. The incidences of recurrence were 4. 6% and 6. 7% in washout group and no-washout group respectively （ X2 = 0. 368, P = 0. 721）. The five-year disease-free survival rate was 79. 7% in washout group and 74. 7% in no-washout group（x2 = 0. 517, P = 0. 553）. Conclusions Free malignant cells were ubiquitous in rectal lumen during anterior resection, and there was a high positive rate of cytological examine for washout sample. Rectal washout may reduce local recurrence and prolong patients survival.
出处
《中华普通外科杂志》
CSCD
北大核心
2013年第6期417-420,共4页
Chinese Journal of General Surgery
关键词
直肠肿瘤
结直肠外科手术
细胞学
肿瘤复发
局部
Rectal neoplasms
Colorectal surgery
Cytology
Neoplasm recurrence, local
作者简介
通信作者：周志祥，E—mail：zhouzx01@Yahoo．com．cn
