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猪肺炎支原体概述及疫苗研究进展 被引量:5

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摘要 一.猪肺炎支原体在养猪业中的现状 呼吸系统疾病是影响猪只健康的最重要的问题之一。猪地方性肺炎的主要病原是猪肺炎支原体,属于一种慢性呼吸系统疾病。猪肺炎支原体在全球养猪业的感染情况非常普遍,大约38%~100%不等,而且会造成重大的经济损失(ThackerandMinion,2010)。
出处 《兽医导刊》 2013年第6期67-72,共6页 Veterinary Orientation
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  • 1冯志新,刘茂军,熊祺琰,华利忠,王海燕,甘源,韦艳娜,苏国东,邵国青.猪支原体肺炎活疫苗(168株)肺内免疫机制研究[J].中国兽药杂志,2012,46(8):4-7. 被引量:8
  • 2刘志宗,张映.猪支原体肺炎疫苗的研究进展[J].中国兽药杂志,2006,40(8):38-40. 被引量:6
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  • 6DEUTSCHER A T,JENKINS C,MINION F C,et al.Repeat regions R1and R2in the P97paralogue Mhp271of Mycoplasma hyopneumoniae bind heparin,fibronectin and porcine cilia[J].Mol Microbiol,2010,78(2):444-458.
  • 7FAUST R O,MAXIMILIEN A,NEDZAD M,et al.Potential use of a recombinant replication-defective adenovirus vector carrying the C-terminal portion of the P97adhesin protein as a vaccine against Mycoplasma hyopneumoniae in swine[J].Vaccine,2010,28:4802-4809.
  • 8YOUNG T F,THACKER E L,ERICKSON B Z,et al.A tissue culture system to study respiratory ciliary epithelial adherence of selected swine mycoplasmas[J].Vet Microbiol,2000,71(3):269-279.
  • 9STRAIT E L,MADSED M L,MINION F C,et al,Real time PCR assays to address genetic diversity among strains of Mycoplasma hyopneumoniae[J].J Clin Microbiol,2008,46(8):2491-2498.
  • 10BOGEMA D R,DEUTSCHER A T,WOOLLEY L K,et al.Characterization of cleavage events in the multifunctional cilium adhesin Mhp684(P46)reveals a mechanism by which Mycoplasma hyopneumoniae regulates surface topography[J].AM Soc Microbiol,2012,3(2):e00282-11.

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