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凝血因子Ⅸ在CHO细胞中的表达和鉴定

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摘要 人类B型血友病,是一种由于不能合成正常凝血因子Ⅸ(hVⅨ)所引起的遗传性疾病。补充hFⅨ是控制此种疾病最有效的方法。本文用CHO细胞作为表达系统,pcDNA3.1作为表达载体表达hFIX。经过对细胞进行免疫组化和免疫荧光分析,证明构建的细胞株表达了重组hFIX蛋白。
出处 《国际医药卫生导报》 2013年第10期1481-1484,共4页 International Medicine and Health Guidance News
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参考文献8

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