摘要
目的探讨对苯丙酮尿症儿童康复干预的效果，从而寻求出最佳的干预模式。方法将2002年1月至2009年10月期间在西安市妇幼保健院筛查出的苯丙酮尿症儿童，采用自愿原则将研究对象分为医院模式（模式1）、医院与家庭相结合模式（模式2）、将不需要饮食治疗的患儿定为家庭模式（模式3）；对照组为随机抽取来西安市妇幼保健院健康体检的儿童。对模式1和模式2患儿进行语言康复、内科推拿、感觉统合训练、智力训练，干预时间为1年，康复干预前、后对目标儿童用Gesell量表行智能发育测评。结果模式1和模式2的患儿干预训练前比较和干预训练后再比较无显著性差异（均P〉0．05）；模式1和模式2的患儿干预训练前、后自身比较发现在语言方面有显著性改善（t=-2．688，P〈0．05；t=-2．085，P〈0．05），其它未见差异。与对照组儿童相比，模式1和模式2的儿童五大能区都有显著性差异（均P〈0．05），模式3的儿童除个人-社交外都存在显著性差异（均P〈0．05）。结论对苯丙酮尿症儿童康复采取医院与家庭相结合的干预模式（模式2）值得推广。
Objective To explore the intervention effects on children with phenylketonuria （PKU） so as to search a best intervention mode. Methods From January 2002 to October 2009 children with PKU screened in Maternal and Child Health Hospital in Xi＇ an were divided into three groups according to voluntary principle. One group was treated with hospital mode （ mode 1 ） , another group with hospital combined with family mode （ mode 2）, and the third group with family mode without needing dietary therapy （ mode 3 ）. Control group were randomly selected children who took health examination in the hospital. Language rehabilitation, massage, sensory integration training and intelligence training were provided in mode 1 and mode 2, and the intervention period was 1 year. Gesell scale was used to evaluate the intelligence of objects before and after intervention. Results There were no significant differences between mode 1 and mode 2 both before and after intervention （ all P 〉 0.05 ）. The difference in language was significant before and after intervention in mode 1 （ t = - 2. 688, P 〈 0.05）, so was in mode 2 （t = - 2. 085, P 〈 0.05 ）. But there was no difference in other aspects between two modes. Compared with control children, there were significant differences in five function areas in mode 1 and mode 2 （ all P 〈 0.05）, and the difference was also significant in mode 3 except for personnel - social contact （ all P 〈 0.05 ）. Conclusion Mode 2 is worthy to be popularized for children with PKU.
出处
《中国妇幼健康研究》
2013年第2期185-187,共3页
Chinese Journal of Woman and Child Health Research
关键词
苯丙酮尿症
康复
干预模式
儿童
phenylketonuria （PKU）
recovery
intervention mode
children
作者简介
曹春红（1979-），女，医师，硕士，主要从事儿童营养及高危儿康复的研究。
[通讯作者]梁艳，主任医师。
