摘要
目的评价生脉注射液治疗缺血性中风急性期的疗效及安全性。方法搜集相关随机对照试验,筛选合格研究,评价纳入研究质量,运用异质性检验、Meta分析、漏斗图分析等方法统计相关数据。结果 Meta分析显示,总有效率比较的合并RR(99%CI)为1.15(1.05,1.27);NNT(99%CI)为8.33(5,25);神经功能缺损、日常生活活动能力评分比较的WMD(99%CI)分别为-6.17(-8.02,-4.32)、-6.09(-11.68,-0.50)。结论生脉注射液可改善缺血性中风急性期患者的神经功能缺损状况,且安全性较高。
Objective： To evaluate the efficacy and safety of Shengmai Injection for acute ischaemic stroke. Methods： Randomized controlled trails （RCTs） of shenginai injection for acute ischaemic stroke were identified, eligible studies were included, the methodological quality of inclusive trails was assessed by Jadad scale. Heterogeneity test, Meta-analysis, funnel plot analysis and sensitivity analysis were used to analyse data. Results： Metaanalysis indicated that relative risk of overall effective rate was 1.15 [ 99%CI （ 1.05,1.27 ） ], NNT （99%CI） was 8.33 （5,25）, WMD （99%CI） of Neural function defect score was -6.17 （-8.02, -4.32）, WMD （99%CI） of Activities of daily living score is -6.09 （-11.68,-0.50）. Conclusion： This systematic review shows that shengmai injection is effective for acute iscbaemic stroke.
出处
《中国中医急症》
2013年第5期696-697,718,共3页
Journal of Emergency in Traditional Chinese Medicine
基金
国家自然科学基金资助项目(30801458)
关键词
生脉注射液
缺血性中风
急性期
随机对照试验
系统评价
Shengmai injection
Ischemic stroke
Acute ischaemic stroke
Randomized controlled trail
Systematic review
