摘要
目的:对头孢呋辛不良反应报告中不合理用药情况进行分析,为进一步规范临床合理用药提供参考。方法:采用回顾性统计分析方法,对武汉市药品不良反应(ADR)监测中心2009~2010年收集的107份头孢呋辛ADR报告,参考药品说明书等对报告中不合理用药情况进行分析。结果:107例ADR/ADE报告中,给药方法不合理102例(95.33%),超药品说明书中推荐剂量用药28例(26.17%),无指证用药11例(10.28%)。结论:头孢呋辛不合理用药情况较严重,应加强ADR的监测与报告,合理使用头孢呋辛,减少或避免ADR/ADE的发生。
Objective:To analyze the irrational use of cefuroxime from adverse drug reaction(ADR) reports. Methods:A retrospective study was used based on the data of cefuroxime obtained in 30 hospitals from Wuhan Adverse Drug Reactions(ADR) Monitoring Center database over a 2-year period from January 2009 to December 2010.Results:Of 107 cases of ADR/ADE,the numbers of misadministration were 102(95.33%),those of overdose,28(26.17%) and no certification medication,11(10.28%).Conclusion;The irrational use of cefuroxime was more serious;therefore,surveillance should be successfully strengthened to optimize the rational use of cefuroxime to reduce or avoid the occurrence of ADR.
出处
《药物流行病学杂志》
CAS
2013年第3期123-125,共3页
Chinese Journal of Pharmacoepidemiology
关键词
头孢呋辛
药物不良反应
合理用药
Cefuroxime
Adverse drug reactions
Rational drug use