期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

半连续切片角蛋白IHC检测口腔鳞癌颈淋巴结隐匿性转移的研究

Application of Semi-continuous of Cyokeratin Immunohistochemistry to Detect Occult Metastasis Cervical Lymph Nodes of Oral Squamous Cell Carcinoma
在线阅读 下载PDF
导出
摘要 目的:比较半连续切片角蛋白IHC和常规H-E染色检测口腔鳞癌颈淋巴结隐匿性转移的精确度。方法:45例口腔鳞癌患者单侧颈清淋巴结2260粒,分别用HE染色和半连续切片IHC检测。结果:IHC和HE检测阳性率分别是31.11%和11.11%(P<0.05)。结论:半连续切片角蛋白IHC技术可应用于口腔鳞癌颈淋巴结隐匿性转移的检测。 Objective： To compare semi-continuous sections of cytokeratin（AE1/AE3） immunohistochemistry and routine HE staining on detection oral squamous cell carcinoma of cervical lymph node metastasis accuracy.Methods： We collected 2260 unilateral neck dissection lymph nodes in 45 patients with oral squamous cell carcinoma.Traditional HE staining and semi-continuous sectiongs of CK（AE1/AE3） immunohistochemical staining were used.Results： Semi-continuous cytokeratin CK（AE1/AE3） immuneohistochemical staining and HE staining for detection of occult cervical lymph node metastasis rate was 31.11%（14/45） and 11.11%（5/45） respactively（P＆lt;0.05）.Conclusion： Semi-continuous sections cytokeratin CK（AE1/AE3） immunohistoch emical detection techniques can be applied to oral squamous cell carcinoma of occult cervical lymph node metastasis detection.
作者 习利军 陈坤 张铁柱
机构地区 深圳市福田区中医院口腔科 广东医学院
出处 《口腔医学研究》 CAS CSCD 2013年第4期358-359,362,共3页 Journal of Oral Science Research
基金 口腔鳞癌隐匿性颈淋巴结转移的检测及临床应用研究 2008[98]
关键词 口腔 鳞状细胞癌 免疫组化 隐匿性转移 颈淋巴结 Oral cavity Squamous cell carcinoma Immunohistochemistry Occult metastasis Lymph nodes
分类号 R739.8 [医药卫生—肿瘤]
作者简介 习利军（1980-），男，江西人，硕士，医师，主要从事口腔科临床治疗工作。 通讯作者 陈坤，电话：0755—83548601
  • 相关文献

参考文献11

  • 1C.Larsson, S.El Madhoun, A.Wennerberg, et al.Frac-ture strength of yttria - stabilized tetragonal zirconia poly-crystals crowns with different design: an in vitro study.OralImpl.Res.xx, 2011,000 - 000.doi : 10.1111/j.1600 -0501.2011.02224.x.
  • 2Yuji KOKUBO, Mitsuyoshi TSUMITA, Takamitsu KANO,et al.The influence of zirconia coping designs on the fractureload of all-ceramic molar crowns [J].Dent Mater J,2011,30(3) : 281 - 285.
  • 3Martin Rosentritt,Daniela Steiger, Michael Behr,et al.Influ-ence of substructure design and spacer settings on the in vitroperformance of molar zirconia crowns [J].J Dent, 2009,37:978 - 983.
  • 4A.SUNDH,G.SJO GREN.A comparison of fracturestrength of yttrium - oxidepartially - stabilized zirconia ce-ramic crowns with varying core thickness, shapes and veneerceramics [J].J Oral Rehabil, 2004,31 :682 - 688.
  • 5De Jager N,Pallav P, Feilzer AJ.The influence of design pa-rameters on the FEA-determined stress distribution in CAD- CAM produced all -ceramic dental crowns [J].Dent Ma-ter, 2005,21 : 242 - 251.
  • 6Aboushelib MN, Kleverlaan CJ, Feilzer AJ.Microtensilebond strength of different components of core veneered allce-ramic restorations.Part II; Zirconia veneering ceramics [J].Dent Mater, 2006,22 : 857 - 863.
  • 7Lawn BR, Deng Y,Lloyd IK, et al.Materials design of ce-ramic- based layer structures for crowns [J].J Dent Res,2002,81 : 433-438.
  • 8Lawn BR, Pajares A, Zhang Y,et al.Materials design in theperformance of all -ceramic crowns [J].Biomaterials, 2004,25 : 2885 - 2892.
  • 9刘亦洪,冯海兰,包亦望,邱岩.基底瓷与饰瓷的厚度比对IPS EmpressⅡ热压铸陶瓷抗弯强度的影响[J].北京大学学报（医学版）,2007,39(1):64-66. 被引量：8
  • 10Wakabayashi N,Anusavice KJ.Crack initiation modes in bi-layered alumina/porcelain disks as a function of core/veneerthickness ratio and supporting substrate stiffness [J].J DentRes, 2000,79 : 1398 - 1404.

二级参考文献14

  • 1Cvar JF, Ryge G. Reprint of criteria for the clinical evaluation of dental restorative materials, 1971 [J]. Clin Oral Invest, 2005, 9(4): 215--232.
  • 2Tsai YL, Petsche PE, Anusavice KJ, et al. Influence of glass --ceramic thickness on Hertzian and bulk fracture mechanisms []]. Int Prosthodont, 1998, 11(1) : 27--32.
  • 3Wolfart S, Ludwig K, Uphaus A, et al. Fracture strength of all--ceramic posterior inlay--retained fixed partial dentures [J]. Dent Mater, 2007, 23(12) :1513--1520.
  • 4Borchers L, Stiesch M, Bach FW, et al. Influence of hydro- thermal and mechanical conditions on the strength of zirconia [J]. Acta Biomater, 2010, 6(12) : 4547--4552.
  • 5Tsitrou EA, Northeast SE, van Noort R. Evaluation of the marginal fit of three margin designs of resin composite crowns using CAD/CAM [J] .J Dent, 2007, 35(1) : 68--73.
  • 6Nakamura T, Dei N, Kolima T, et al. Marginal and internal fit of CEREC3 CAD/CAM all-ceramic crowns [J]. Int J Prosthodont, 2003,16(3) :244--248.
  • 7Zeng K,Odén A,Rowcliffe D.Evaluation of mechanical properties of dental ceramic core materials in combination with porcelain[J].Int J Prosth,1998,11:183-189.
  • 8Hopkins K.An investigation into the role of porcelain thickness in determining the load carrying capacity of porcelain laminates[J].Br dent J,1989,167:201-204.
  • 9McCabe JF,Carrick TE.A statistical approach to the mechanical testing of dental materials[J].Dent Mater,1986,2:139-142.
  • 10Fleming GJP,El-Lakwah SFA,Harris JJ,et al.The influence of interfacial surface roughness on bilayered ceramic specimen performance[J].Dent mater,2004,20:142-149.

共引文献8

口腔医学研究
2013年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
关于我们 | 版权声明 | 联系我们 | 帮助中心| 意见反馈
主办单位：上海市教育委员会
技术支持：重庆维普资讯有限公司
渝公网安备 50019002500403号
使用帮助 返回顶部