摘要
目的通过对非处方中成药不良反应发生原因的归纳总结,为非处方中成药的安全合理使用提供参考。方法规定中成药范围包括:中药复方制剂,中西药复方制剂,中药提取物制剂。采用回顾性研究方法,通过检索检索国家食品药品监督管理局药品不良反应监测中心、药物不良反应杂志和CNKI中文数据库,对有不良反应发生情况的常用非处方中成药进行总结归纳,分析不良反应发生的原因。结果影响非处方药不良反应的因素主要有药物因素、联合用药、药证不符、体质因素、用药不当、含有有毒中药、"中药西化"不成熟。结论非处方药的不良反应与诸多因素有关,建议临床应用,充分考虑各个方面,加大对不良反应的监测与报道,完善不良反应发生机制的研究,为非处方药的安全使用提供参考。
Objective By summarizing the causes of adverse reaction of nonprescription Chinese medicine,we provide a reference for the safe use of Nonpreseription Chinese medicine. Methods Set the scope of Chinese medicine：Traditional Chinese medicine,Traditional Chinese and Western Medicine,The preparation of Chinese medicine extract. Use the research methods in regression,by retrieving it in National Center for ADR Monitoring of State Food and Drug Administrati0n,Adverse Drug Reactions Journal and Chinese Journal Full Database,summarizing the nonpreseription Chinese medicine which have adverse reaction and analyzing the causes of adverse reaction. Results There are many factors influencing the adverse reaction of nonpreseription Chinese medicine, such as drug factors,combination therapy,the distinctive between drugs and syndromes, physical factors,inappropriate medication,including toxic Chinese medicine,immature of Chinese medicine westernized. Conclusion The adverse reaction of nonprescription Chinese medicine related to many factors. In clinical application,we advise that giving full consideration to all aspects of it, increasing the monitoring and report of adverse reaction and consummating the research of adverse reaction mechanism, provide a reference for the safe use of nonoreseription Chinese medicine.
出处
《云南中医学院学报》
2013年第2期47-49,55,共4页
Journal of Yunnan University of Traditional Chinese Medicine
基金
北京中医药大学科研创新团队资助项目(NO:2011-CXTD-14)
关键词
非处方药
中成药
不良反应
影响因素
Nonprescription drugs
Chinese medicines
adverse reactions
influencing factors
作者简介
王璞（1959～），女，山东淄博人届0教授，研究方向：非处方药不良反应。
