摘要
联合用药已经广泛地运用于多种疾病的治疗过程中,如抗菌、抗病毒、抗肿瘤等治疗领域。然而,目前为止国内外学者关于联合用药后疗效的评价标准仍没有达成一致,尤其是药物协同作用的评价。Chou-Talalay是目前被广泛认可的药物协同作用定量分析方法。本文针对抗肿瘤研究领域,对该法的研究应用概况作一综述,为合理用药的研究提供线索和参考。
Drug combination has been widely used in the therapeutic process of many serious illness, such as anti-bacterial, anti-viral and anti-tumor therapeutic, etc. However, so far the domestic and overseas scholars about evaluation standards of the curative effects have not arrived at any agreement yet, especially the synergistic effect of drug combination. Chou-Talalay method is now generally accepted as synergy quantitative analysis method for drug combination. Aiming at the anti-tumor research field, we comprehensively reviewed the method to lay a good basis for the rational use of drugs.
出处
《中国现代应用药学》
CAS
CSCD
2013年第4期449-453,共5页
Chinese Journal of Modern Applied Pharmacy
作者简介
王士群，男，硕士生Tel：（0759）2388405 E-mail：731560548@qq．com
通信作者：郑学宝，男，博士，教授，博导Tel：（0759）2388405 E—mail：xuebaozheng@163．com
