摘要
目的探讨缬沙坦氢氯噻嗪片对老年原发性高血压的疗效和治疗安全性。方法将2010年1月～2012年10月佛山市顺德区北!医院收治的82例老年原发性高血压患者随机分为实验组和对照组,各41例。对照组给予缬沙坦(每日一次,每次80mg)治疗,实验组采用缬沙坦氢氯噻嗪片(每日一次,每次80mg/12.5mg)治疗,对比两组患者的临床治疗效果,并统计不良反应发生率。结果实验组患者41例,总有效率为90.24%(37/41),高于对照组患者[73.17%(30/41)],差异有统计学意义(P<0.05);实验组患者与对照组患者的不良反应比较差异无统计学意义(P>0.05)。结论临床治疗老年原发性高血压中使用缬沙坦氢氯噻嗪片治疗,效果明显,安全性高,是一种有效的治疗药物。
Objective To evaluate the efficacy and security of valsartan/hydrochlorothiazide in treatment of elderly patients with essential hypertension. Methods January 2010 to October 2012, Foshan Shunde Beijiao hospital treated 82 elderly patients with essential hypertension were randomly divided into the experimental group and the control group, 41 cases in each. The control group received valsartan （once-daily dose of 80 rag） treatment, the experimental group, valsartan hydrochlorothiazide tablets （once daily treatment dose 80 mg/12.5 mg）, and compare the clinical outcomes of the two groups of patients, and Statistics The incidence of adverse reactions.Results The total effective rate of the experimental group was 90.24% （37/41）, which was higher than that of the control group, the difference was statistically significant, P〈0.05; adverse reactions was not significantly different in the experimental group and the control group ,P〉0.05. Conclusion The clinical treatment of elderly patients with essential hypertension with valsartan / hydrochlorothiazide therapy, the effect is obvious, high security, is an effective therapy.
出处
《当代医学》
2013年第12期142-143,共2页
Contemporary Medicine
关键词
老年
原发性高血压
缬沙坦
氢氯噻嗪
Elderly
Essential hypertension
Valsartan
hydrochlorothiazide
