摘要
目的研究介入化疗联合放射治疗原发性巨块型肝癌的临床疗效及毒副作用。方法对65例患者先行介入化疗,随后行三维适形放疗。结果治疗后完全缓解15例,部分缓解35例,无变化7例,1、2、3年存活率分别为82.2%、54.5%、30.3%。治疗后部分患者出现副作用,但经处理后均能完成治疗。结论介入化疗联合放疗能提高原发性巨块型肝癌的临床疗效,延长生存期,毒副作用可耐受。
Objective To evaluate the treatment efficency and side effects of interventional chemotherapy with threedimenitonal conformal radiotherapy （3 DCRT）for the treatment of huge liver cancer. Methods 65 patients with huge liver cancer were treated with interventional therapy and 3DCRT. Results The effective rate（ CR ＋ PR） was 76. 9% ,and the survival rate of 1,2,3 years were 82. 2% ,54. 5% ,30. 3%. The main side effects and major toxicity of radiotherapy and chemotherapy were tolerated. Conclusions Intervenitonal therapy with three-dimentional conformal radiotherapy can significantly raise the effective rate and survival rate.
出处
《中南医学科学杂志》
CAS
2013年第2期151-153,共3页
Medical Science Journal of Central South China
基金
广西壮族自治区自然科学基金资助(10124001B-7)
关键词
介入化疗
放射治疗
原发性巨块型肝癌
interventional therapy
three-dimenitonal conformal radiotherapy
huge liver cancer
作者简介
李高峰，博士，副主任医师，硕士研究生导师，主要从事肿瘤放射治疗临床研究，E—mail：ligaofeng1000@sina．com．cn．
