期刊文献+

左西孟旦与米力农治疗急性失代偿心力衰竭的疗效比较 被引量:17

原文传递
导出
摘要 目的比较左西孟旦与米力农治疗急性失代偿心力衰竭的临床疗效和安全性。方法选取急性失代偿性心力衰竭患者共85例。随机分为观察组和对照组,在两组均给予常规药物治疗基础上,观察组静脉滴注左西孟旦,对照组静脉滴注米力农。结果观察组治疗总有效率为83.72%,明显高于对照组的71.43%(P〈0.01)。对照组不良反应发生率(19.05%)显著高于观察组(11.63%)(P〈0.05)。结论左西孟旦在治疗重度失代偿性心力衰竭的临床效果优于米力农,且不良反应低,临床可进一步推广使用。
出处 《中国基层医药》 CAS 2013年第8期1194-1195,共2页 Chinese Journal of Primary Medicine and Pharmacy
  • 相关文献

参考文献6

二级参考文献38

  • 1杨迅.米力农治疗慢性肺心病合并心力衰竭疗效观察[J].中外医疗,2008,27(18). 被引量:9
  • 2Antoniades C, Tousoulis D, Koumallos N, et al. Levosimendan:beyond its simple inotropic effect in heart failure [J].Pharmacol Ther, 2007, 114 (2): 184-197.
  • 3Antila S, Sundbcrg S, Lehtonen LA. Clinical pharmacology of levosimendan [J].Clin Pharmacokinet, 2007, 46 (7): 535- 552.
  • 4Ikonomidis I, Parissis JT, Paraskevaidis I, et al. Effects of levosimendan on coronary artery flow and cardiac performance in patients with advanced heart failure [J]. Eur J Heart Fail, 2007, 9 (12): 1172-1177.
  • 5Parissis JT, Andreadou I, Bistola V, et al. Novel biologic mechanisms of levosimendan and its effect on the failing heart [J].Expert OpinInvestig Drugs, 2008, 17 (8): 1143-1150.
  • 6Parissis JT, Adamopoulos S, Antoniades C, et al. Effects of levosimendan on circulating pro inflammatory cytokines and soluble apoptosis mediators in patients with decompensated advanced heart failure [J].Am J Cardiol, 2004, 93 (10):1309-1312.
  • 7Farmakis D, Parissis JT, Bistola V, et al. Plasma B-type natri uretic peptide reduction predicts long-term response to levosimendan therapy in acutely deeompensated chronic heart failure [J] Int J Cardiol, 2010, 139 (1): 75-79.
  • 8Tziakas DN, Chalikias GK, Hatzinikolaou HI, et al. Levosimendan use reduces matrix metalloproteinase-2 in patients with decompensated heart failure [J]. Cardiovasc Drugs Ther, 2005, 19 (6): 399-402.
  • 9Parissis JT, Andreadou I, Markantonis SL, et al. Effects of levosimendan on circulating markers of oxidative and nitrosative stress in patients with advanced heart failure [J]. Atherosclerosis, 2007, 195 (2): e210-e215.
  • 10Parissis JT, Karavidas A, Bistola V, et al. Effects of levosimendan on flow mediated vasodilation and soluble adhesion molecules in patients with advanced chronic heart failure [J]. Atherosclerosis, 2008, 197 (1): 278-282.

共引文献52

同被引文献141

  • 1蔡及明,杨艳敏,陈玲.米力农治疗心力衰竭和肺动脉高压的研究进展[J].国外医学(儿科学分册),2005,32(6):375-377. 被引量:31
  • 2慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17. 被引量:8245
  • 3姜正华,吕元文,桑慧颖,朱慕云,朱湘平,丁平.慢性呼吸衰竭患者血栓前状态的研究[J].中华急诊医学杂志,2007,16(1):75-77. 被引量:15
  • 4苏轮,李彬,孙沛,陈昕,白秉学,李晓利,薛俊仙,张金花,武若君,王亚真.低分子肝素联合阿司匹林治疗老年不稳定型心绞痛的临床观察[J].中西医结合心脑血管病杂志,2007,5(9):891-892. 被引量:3
  • 5陈灏珠.心脏病学[M].5版.北京:人民卫生出版社,2000:1715-1739.
  • 6Nieminen MS,Bohm M,Cowie MR,et al.Executive summary of theguidelines on the diagnosis and treatment of acute heart failure:theTask Force on Acute Heart Failure of the European Societ y ofCardiology[J],Eur Heart J,2005,26(4):384-416.
  • 7Follath F,Cleland JG,Just H,et al.Efficacy and safety ofintravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study ):a randomised double-blindtrial[J].Lancet,2002,360(9328):196-202.
  • 8Mebazaa A,Nieminen MS,Packer M,et al.Levosimendan vsdobutamine for patients with acute decompensated heart failure:theSURVIVE Randomized Trial[J].JAMA,2007,297 ( 17 ):1883-1891.
  • 9Delaney A,Bradford C,McCaffrey J,et al.Levosimendan for thetreatment of acute severe heart failure:A meta-analyses ofrandomized controlled trials[J].Int J Cardiol,2010,138(3):281-289.
  • 10Ribeiro JRA,Rohde LE,Polanczyk CA,Levosimendan in acutedecompensated heart failure:systematic review and meta-analysis[J].Arq Bras Cardiol,2010,95(2):230-237.

引证文献17

二级引证文献63

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部