摘要
目的：探讨3．0T 3D TOF MRA对颅内血管狭窄术前评估的可靠性。方法：哈尔滨医科大学附属二院30例颅内动脉狭窄患者，均行3．0T 3D TOF MRA和旋转数字减影血管成像（DSA）检查。分析30例患者的450个血管片段。以DSA为诊断标准，以有无狭窄、轻度狭窄（10％-〈50％）、狭窄50％、70％、100％为判定点计算敏感性、特异性、阳性预测值（PPV）及阴性预测值（NPV）。结果：共发现115段病变血管，MRA发现狭窄的敏感性、特异性分别为87．0％和99．7％；以50％为界点分别是86．7％和99．5％，PPV92．9％和NPV99．1％；以70％为界点分别是95．5％、99．5％、PPV91．3％和NPV99．5％。8处闭塞MRA诊断出7处，假阳性、假阴性各1处（分别是基底动脉和椎动脉颅内段）。28段（24．6％）高估，7段低估。结论：对于判定50％、70％颅内动脉狭窄，3．0T 3D TOF MRA与旋转DSA相比具有较高的敏感性及特异性，可作为支架置入术前一种有效的检查手段。
Objective： To explore the reliability of 3D TOF MRA on 3.0T MR system for preoperative assessment of in- tracranial vascular stenosis. Methods： Thirty patients with intracranial arterial stenosis in the 2nd Hospital Affiliated to Harbin Medical University, who received both 3D TOF MRA on a 3.0T MR system and rotational digital subtraction angiography examinations. 450 vascular segments of the 30 patients were analysed. Without stenosis, mild stenosis （10%-〈50%）, stenosis of 50%, 70%, 100% as decision point to calculate sensitivity, specificity, positive predictive value （PPV） and negative predictive value （NPV） of MRA. Results： Compared to DSA, 115 lesions were detected, the sensitivity and specificity were 87.0% and 99.7% for MRA in detecting stenosis. Take 50% as the critical point. The sensitivity and specificity was 86.7% and 99.5% respectively, the PPV was 92.9% and the NPV was 99.1%. Take 70% as the critical point the sensitivity and specificity was 95.5%, 99.5% respectively, PPV 91.3% and NPV 99.5%. MRA diagnosed 7 in the eight occlusions. One false positive and one false negative（that was stenosis of the basilar artery and intracranial segment of the vertebral artery）. Twenty-eight（24.6%） segments were overestimated, 7 segments were underestimated. Conclusion： To determine 50% and 70% intracranial arterial stenosis, 3.0T 3D TOF MRA has high sensitivity and specificity compared to rotational DSA, and can be used as an effective means in pre-stenting surgery.
出处
《中国临床医学影像杂志》
CAS
2013年第3期153-158,共6页
Journal of China Clinic Medical Imaging
关键词
动脉硬化
血管造影术
数字减影
磁共振血管造影术
Arteriosclerosis
Angiography, digital subtraction
Magnetic resonance angiography
作者简介
孙静（1982-），女，山东枣庄人，医师。
