摘要
回顾性分析220例无功能细胞瘤。病例确诊依赖于“三无”：免疫组化阴性染色；无血浆激素水平升高；无激素升高引起的相应症状。发生率占同期垂体瘤的首位（33.13%），男∶女为132∶88，老年前期发生率最高（50%～65.91%）。临床特征为（1）卒中发生率高（38.18%），（2）主要压迫症状包括视野异常（85.00%），头痛（80%），视力下降（68.66%）及垂体功能低下症状（44.04%）等。影像特点有（1） 2～4 cm者占71.82%，（2）侵袭Ⅲ、Ⅳ级者达83.64%。
A retrospective analysis was carried out in 220 cases of nonfunctional pituitary adenoma（NFA）. The diagnosis was based on negative immunohistochemical staining, no elevation of plasma hormone level, and no symptom caused by increased hormone level. Incidence of NFA was the highest（33.13%） among the pituitary tumors. It was more common in males than in females（132∶88）. The highest prevalence resided in the elder group. NFA often caused pituitary apoplexy, and mainly presented as compression symptoms including visual field abnormalities（85.00%）, headache（80%）, hypopsia（68.66%）, and other symptoms of hypopituitarism（44.04%）. Imaging features showed tumor size usually within 2-4 cm（71.82%）, and aggregated degree Ⅲ or Ⅳ（83.64%）.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2013年第2期155-156,共2页
Chinese Journal of Endocrinology and Metabolism
关键词
无功能垂体瘤
免疫组化染色
临床识别
Nonfunctional pituitary adenoma
Immunohistochemistry
Clinical identification
作者简介
通信作者：刘国良,Email：liuguoliang824@yahoo．cn
