摘要
目的探讨视网膜静脉阻塞(RVO)与颈动脉狭窄的相关性。方法选RVO患者68例(68只眼)进行颈部彩色多普勒超声检查,包括检测颈动脉斑块、颈总动脉内膜-中层厚度、颈内动脉血流速,与正常对照组49例(49只眼)比较。结果患眼同侧及对侧颈动脉诸测值比较无统计学差异(P>0.05)。患者颈总动脉内膜-中层厚度(IMT)显著增加,颈内动脉收缩期峰值血流速度(PSV)和舒张末期血流速度(EDV)显著降低,阻力指数(RI)明显增高,与眼别、性别病程无明显差异。患者颈动脉斑块以颈总动脉分叉处最多见,左侧多于右侧。部分静脉淤滞性视网膜病变(VSR)患者的各测值6个月后均有回升,而出血性视网膜病变(HR)者却不变。早期综合治疗对部分VSR患者预后有利。结论 RVO患者颈动脉狭窄发病率高,颈部彩色多普勒超声检查可以客观地间接反映视网膜供血状况,可作为RVO的病情、预后及疗效观察的参考依据。对预防缺血性脑卒中也有一定的临床意义。
Objective To investigate the correlation between retinal vein occlusion and carotid artery stenosis. Methods Sixty-eight patients （68 eyes ） with retinal vein occlusion were studied. Subjects were examined by color Doppler ultrasonography for carotid artery plaque, common carotid artery intima-media thickness, and internal carotid artery blood flow velocity. Forty-nlne healthy subjects （ 49 eyes ） were enrolled as control. Results Increased intima-media thickness （IMT） of common carotid artery was found in patients with retinal vein occlusion （ P 〈0.01 ）. Both peak systol- ic velocity （PSV） and end diastolic velocity （EDV） of internal carotid artery reduced significantly （ P 〈0.01 }, while re- sistance index （RI） increased significantly （P 〈0.01）. Differences in gender, ocular side, disease course, and carotid artery side have no effect on these measurements. The plaques are mere commonly observed in the crotch of common carotid artery, especially on the left side. These changes exhibited a later recovery in venous stasis retinopathy （VSR） patients, but not in hemon＇hagic retinopathy （ HR ） patients. Our results also showed that the combined therapy at early stage was very important to improve prognosis in some patients with venous stasis retinopathy（VSR ）. Conclusion The incidence of carotid artery stenesis is high in patients with retinal vein occlusion. Color Doppler ultmsonography of carotid artery indi- rectly measures the status of retinal blood-supply and may be a reference for disease condition, prognosis and treatment out- comes. It also has some clinical value for cerebral arterial thrombosis prevention.
出处
《临床眼科杂志》
2013年第1期19-22,共4页
Journal of Clinical Ophthalmology
关键词
视网膜静脉阻塞
彩色多普勒超声检查
颈动脉粥样硬化
颈动脉狭
颈动脉斑块
Retinal vein occlusion
Color Doppler ultrasonography
Carotid artery atherosclerosis
Carotid arterystenosis
Carotid artery plaque
作者简介
通讯作者：丁慰祖（Email：dwz343@yahoo．com．cn）
