摘要
目的:观察甲状腺功能减退症(甲减)、亚临床甲状腺功能减退症(亚临床甲减)患者和正常人血清游离甲状腺素(FT4)与血脂水平变化之间的关系。方法:测定100例甲减、100例亚临床甲减患者和100例正常人血清中FT4、总胆固醇(TC)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、甘油三酯(TG)水平,并进行三组对比研究。结果:三组比较,甲减组和亚临床甲减组与正常组比较TC、LDL、TG水平有显著性差异(P<0.01);甲减组和亚临床甲减组比较TC、LDL、TG水平有明显差异(P<0.05);相关性分析TC、LDL、TG随着游离甲状腺素升高而下降,它们之间有着密切的相关性。结论:FT4是敏感反映甲状腺功能状态的指标,对诊断亚临床甲减和甲减具有指导意义;FT4升高是影响甲减和亚临床甲减患者血脂升高的主要因素之一;甲减组与亚临床甲减组之间TC、LDL、TG水平有明显差异。
Objective：To observe the hypothyroidism（JiaJian）,and clinical hypothyroidism（and clinical JiaJian） and patients with normal serum free thyroxine（FT4） and lipid levels of the relationship between the changes.Methods：100 cases were JiaJian and 100 cases and clinical JiaJian patients and 100 patients with normal serum FT4（TC）,total cholesterol,low-density lipoprotein（LDL）,high-density lipoprotein （HDL）,triglycerides（TG） level,and three groups of comparative study.Results：The three groups of comparison,JiaJian group and the clinical JiaJian group group compared with normal TC,LDL,TG level significant difference（P0.01）;JiaJian group and the clinical JiaJian group compared TC,LDL,TG level have obvious difference（P0.05）;The correlation analysis TC,LDL,TG with free thyroxine rise,has close correlation between them.Conclusion：FT4 are sensitive to reflect the state of the thyroid function indexes of clinical diagnosis and JiaJian JiaJian and has a guiding significance;FT4 increase is JiaJian influence and the clinical JiaJian patients increased blood fat one of the main factors;JiaJian group and the clinical JiaJian group TC,between LDL,TG level have obvious difference.
出处
《中国医药导刊》
2012年第12期2104-2105,共2页
Chinese Journal of Medicinal Guide
