摘要
目的探讨超声造影在眼眶肿瘤良恶性病变鉴别诊断中的应用价值。方法对47例眼眶肿瘤患者47个病灶（良性组35例，恶性组12例）进行术前常规超声和超声造影检查，观察肿瘤超声造影的特征，应用SonoLiver分析软件进行后处理得到肿瘤造影时间-强度曲线（TIC），获取造影剂达到时间（AT）、上升时间（RT）、达峰时间（TTP）、平均渡越时间（mTT）、曲线下面积（AUC）、峰值强度（IMAX）、造影灌注指数（PI）进行定量分析。结果良恶性肿瘤的血流灌注特点不同。时间-强度曲线参数中上升支斜率、半降斜率的绝对值、IMAX、PI、mTT、半洗出时间、RT良恶性间差异有统计学意义（P〈0．05），AT、AUC、TTP差异无统计学意义（P〉0．05）。结论超声造影在眼眶良恶性肿瘤的鉴别诊断中有一定的临床应用价值。
Objective To explore the value of ultrasound-enhanced ultrasound （CEUS） in the differential diagnosis of orbital neoplasms by observing the perfusion characteristics of orbital benign and malignant neoplasms {or the application of ultrasound contrast microbubbles. Methods Preoperative ultrasound imaging of 47 patients with orbital neoplasms（benign group 35 cases, malignant group 12 cases）were observed for the tumor characteristics of CEUS. The parameters of tumor imaging obtained time intensity curve （TIC） were obtained by quantitative analysis of SonoLiver analysis software, which were contrast agent arrive time （AT） ,rise time （RT） ,time to peak （TTP） ,mean transit time （mTT） ,area under the curve （AUC） ,maximum intensity（IMAX） and perfusion index （PI）. Results Different characteristics of perfusion were shown between benign and malignant groups. Time parameters of TIC：rising slope,semidescending slope,IMAX, PI, mTT, semi-washed out time and RT were significantly different between the two groups （P 〈0.05） while there was no significant difference of parameters as AT, TTP, AUC. Conclusions There is certain clinical value of the CEUS in the differential diagnosis of ocular benign and malignant neoplasms,
出处
《中华超声影像学杂志》
CSCD
北大核心
2013年第1期63-66,共4页
Chinese Journal of Ultrasonography
关键词
超声检查
微气泡
眶肿瘤
Ultrasonography
Microbubbles
Orbital neoplasms
作者简介
CHEN Wen-wei ,Email ： wuhancww@126. com
