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选择最佳氧气流量对AECOPD患者实施氧气雾化吸入的临床研究 被引量:6

Clinical Study to Select the Optimal Oxygen Flow Rate for Implementation of Oxygen Inhalation in Patients with AECOPD
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摘要 目的探讨老年AECOPD患者进行氧气雾化吸入疗法时最适宜的氧流量。方法对125例采取氧气雾化吸入疗法的AECOPD患者,按照4L/min,5L/min,6L/min,7L/min,8L/min的氧流量随机分为5组,观察患者雾化吸入前后的心率、末梢脉氧饱和度、患者舒适度及1小时内咯痰量的变化。结果氧气流量为6L/min,患者舒适度得分最高,同时1h咯痰量最多。组间比较,舒适度得分均有差异(P<0.05);6L/min氧流量的1h内咯痰量与4L/min、5L/min比较有明显差异(P<0.05);氧流量4~6L/min时,雾化前后心率变化较小(P>0.05),7~8L/min时,雾化前后心率变化较大(P<0.05);各组雾化后脉氧均明显增加增加(P<0.05)。结论在AECOPD患者进行氧气雾化疗法时,采用氧流量在6L/min,可达到最佳的雾化效果。 Objective To study the optimal oxygen flow rate for implementation of oxygen inhalation in patients with AECOPD.Methods One hundred twenty five AECOPD patients with Oxygen atomization inhalation therapy were randomly divided into five groups according to the oxygen flow rate of 4L/min,5L/min,6L/min,7L/min,and 8L/min separately.The changes of heart rate,peripheral blood oxygen saturation,patient comfort and the expectoration amount within 1 hour were measured.Results The oxygen flow rate of 6L/min results in highest score of patient comport and largest amount of expectoration within one hour.There were difference in comport score among all groups(P 0.05).The expectoration amount within one hour of 6L/min group was significant different from 4L/min and 5L/min group(P 0.05).The heart rate change of pre-and post-inhalation therapy was not statistically significant at the oxygen flow rate of 4-6L/min(P0.05),while at rate of 7~8L/min the change was obvious(P0.05).The pulse oxygen saturation was increased significantly in each group(P0.05).Conclusion The best oxygen flow rate was 6L/min for implementation of oxygen inhalation in patients with AECOPD.
出处 《中国医药指南》 2012年第36期1-1,8,共2页 Guide of China Medicine
基金 全军医学科学技术研究"十二五"计划保健专项课题(11BJZ18)
关键词 氧气雾化吸入 慢性阻塞性肺疾病 氧流量 Oxygen inhalation Chronic obstructive pulmonary disease(COPD) Oxygen flow rate
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