期刊文献+

沙美特罗替卡松联合苏黄止咳胶囊治疗咳嗽变异性哮喘疗效观察 被引量:17

Clinical observation of the effect of salmeterol/fluticasone and Su Huang cough relieve capsule in the treatment of 50 patients with cough variant asthma
在线阅读 下载PDF
导出
摘要 目的观察沙美特罗替卡松(舒利迭)联合苏黄止咳胶囊对咳嗽变异性哮喘(CVA)的治疗效果。方法将50例临床诊断为CVA的患者随机分为两组。A:23例,舒利迭(50/250ug)吸入,每日2次。B:27例,舒利迭(50/250μg)吸入,每日2次,同时口服苏黄止咳胶囊3粒/次,每日3次。2周后比较两组患者的咳嗽症状积分和咳嗽敏感性,4周后比较两周患者的复发率。结果 2周后,与A组比较,B组的咳嗽症状积分(P>0.05)无显著差异,而咳嗽敏感性(P<0.05)降低,4周后,B组总复发率较A组下降。结论舒利迭联合苏黄止咳胶囊治疗能降低CVA患者的咳嗽敏感性,减少复发率。 Objective To investigate the effect of salmeterol/fluticasone and Su Huang cough relieve capsule in the treatment of patients with CVA. Methods 50 patients with CVA were randomly divided into two groups. The group A ( n = 23 ) were given 50 txg of salmeterol and 250 t^g of fluticasone twice a day. The group B ( n = 27 ) were given 3 pills of Su Huang cough relieve capsule once and 3 times a day on the basis of salmeterol/fluticasone (50/250 p^g). The cough symptom score and cough reflex sensitivity were compared after 2 weeks and the relapse rate was compared after 4 weeks. Results After 2 weeks, the difference of cough symptom score between the two groups had no statistical significance (P 〉 0. 05 ), but there was significant difference in cough reflex sensitivity between the two groups ( P 〈 0.05 ). The relapse rate of the group B was lower than that of the group A 4 weeks after. Conclusion The combination therapy of salmeterol/flutleasone and Su Huang cough relieve capsule can reduce the cough reflex sensitivity and relapse rate of patients with CVA.
出处 《临床肺科杂志》 2013年第2期257-258,共2页 Journal of Clinical Pulmonary Medicine
关键词 沙美特罗替卡松 苏黄止咳胶囊 咳嗽变异性哮喘 salmeterol/fluticasone Su Huang cough relieve capsule cough variant asthma (CVA)
  • 相关文献

参考文献10

  • 1Dicpinigaitis PV. Chronic cough due to asthma: ACCP evidence-based clinical practice guide lines [ J] . Chest, 2006,129 ( 1 ) :75 -79.
  • 2刘国梁,林江涛.“不明原因”慢性咳嗽的病因构成和临床特征分析[J].中华结核和呼吸杂志,2009,32(6):422-425. 被引量:147
  • 3美国国立卫生院心、肺、血液研究所(NIILBI).1998年8月1日全球哮喘防治的创议(Global initiative for asthma GINA).
  • 4全国儿科哮喘病协作组.儿童哮喘诊断标准和治疗常规.中华儿科杂志,1993,:222-222.
  • 5陈如冲,赖克方,刘春丽,罗炜,郑劲平,钟南山.辣椒素咳嗽激发试验方法的建立及其安全性评价[J].中华结核和呼吸杂志,2005,28(11):751-754. 被引量:38
  • 6Nakajima T,Nishimura Y,Ishiuma T,et al. Characteristics of patietswith chronic cough who developed classic asthma during the courseof cough variant astha : a longitudinal study [ J]. Respiration, 2005 ,72(6)-.606-611.
  • 7Fujimura M,Hara J,Myou S, Change in brochial responsiveness andcough reflex sensitivity in patients with cough variant asthma : effectof inhaled corticosteroids[ J]. Cough,2005 ,25 :1 -5.
  • 8苗青,魏鹏草.咳嗽变异性哮喘的研究进展[J].实用医学杂志,2011,27(10):1717-1718. 被引量:49
  • 9Takeo Nakajimal, Yoshihiro Nishimural, Temaki Nishiumal, et al.Cough sensitivity in pure cough variant asthma elicited using contin-uous capsaicin inhalation[ J] . Allergology International,2006,55 :149 -155.
  • 10张燕萍,赵丹,林琳,魏葆琳,李素云,徐艳玲,晁恩祥.苏黄止咳胶囊治疗咳嗽变异型哮喘140例临床研究[J].中华中医药杂志,2007,22(11):773-776. 被引量:49

二级参考文献46

  • 1马洪明,朱礼星,赖克方,朱彤,孙宝清,欧阳铭,钟南山.不明原因慢性咳嗽的诊断探讨[J].中华结核和呼吸杂志,2003,26(11):675-678. 被引量:221
  • 2中华医学会呼吸病学分会哮喘学组.咳嗽的诊断与治疗指南(草案)[J].中华结核和呼吸杂志,2005,28(11):738-744. 被引量:1456
  • 3赖克方,陈如冲,刘春丽,罗炜,钟淑卿,何梦章,李德容,钟南山.不明原因慢性咳嗽的病因分布及诊断程序的建立[J].中华结核和呼吸杂志,2006,29(2):96-99. 被引量:390
  • 4Pratter MR. Overview of common causes of chronic cough: ACCP evidence-based clinical practice guidelines. Chest, 2006, 129(1 Suppl) :59S-62S.
  • 5Morice AH. Epidemiology of cough. Pulm Pharmacol Ther, 2002, 15:253-259.
  • 6Chung KF, Pavord ID. Prevalence, pathogenesis, and chronic cough. Lancet, 2008, 371:1364-1374.
  • 7Kohno S, Ishida T, Uchida Y, et al. The Japanese Respiratory Society guidelines/'or management of cough. Respirology, 2006, 11 Suppl 4 : S135-S186.
  • 8Gibson PG, Fujimura M, Niimi A. Eosinophilic bronchitis : clinical manifestations and implications for treatment. Thorax, 2002, 57 : 178-182.
  • 9Gibson PG, Dolovich J, Denburg J, et al. Chronic cough: eosinophilic bronchitis without asthma. Lancet, 1989, 1:1346- 1348.
  • 10Matsumoto H,Niimi A,Tabuena RP,et al.Airway wall thickening in patients with cough variant asthma and nonasthmatic chronic cough[J].Chest J T-Chest,2007,131 (4):1042-1049.

共引文献286

同被引文献173

引证文献17

二级引证文献157

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部