摘要
低蛋白血症是一种常见的临床表现,可影响许多疾病的预后,是预测危重症患儿病死率、发病率的重要指标。血清白蛋白水平与病情严重程度和病死率有密切关系。在儿科临床上,低蛋白血症也被看成是急性感染的一个常见特征。因此,重视危重症患儿的低白蛋白血症,及时给予临床干预对降低病死率有着至关重要的作用。然而目前导致儿童低白蛋白血症的发生机制尚未完全阐明,是否需要白蛋白治疗也仍处于争议中。本文着重阐述儿童低蛋白血症的临床意义、发病机制及其治疗。
Hypoproteinemia is a common clinical manifestation, which could affect prognosis of many diseases. It is an important prediction index of mortality, morbidity in critically ill children. Serum albumin level is closely related to the severity and mortality. In pediatric practice, hypoalbuminemia is also seen as a common feature of acute infection. Therefore, the clinical interventions of hypoalbuminemia in critically ill children should be emphasized, which plays a crucial role in reducing the mor- tality rate. At present, the pathogenesis of hypoalbuminemia has not yet been fully clarified, so the treatment of hypoproteinemia still remains controversy. In this article, the clinical significance, pathogenesis and treatment of childhood hypoalbuminemia arereviewed.
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2012年第11期1088-1090,共3页
Journal of Clinical Pediatrics
关键词
低蛋白血症
发生机制
治疗
儿童
hypoproteinemia
pathogenesis
treatment
children
