摘要
目的双源CT血管造影(dual-source computed tomography angiography,DSCTA)对颅内动脉瘤的诊断已得到了很好的应用,但目前DSCTA诊断烟雾病合并动脉瘤的报道并不多见,文中主要探讨DSCTA在烟雾病合并动脉瘤中的诊断价值。方法 32例同时经数字减影血管造影(digital subtraction angiography,DSA)及DSCTA检查诊断为烟雾病的患者纳入本研究,以DSA诊断为参照标准,评价DSCTA在烟雾病患者中检测动脉瘤的灵敏度、特异度、阳性预测值及阴性预测值。结果 32例患者DSCTA诊断13例患者合并有动脉瘤,2例多发,共15枚;DSA诊断12例患者合并动脉瘤,共13枚,动脉瘤多位于基底动脉环。以DSA诊断为参照标准,DSCTA诊断烟雾病合并动脉瘤的灵敏度、特异度、阳性预测值及阴性预测值以患者为单位分别为100%、95.0%、92.3%、100%,以动脉瘤枚数为单位分别为100%、90.5%、86.7%、100%。结论 DSCTA在诊断烟雾病合并动脉瘤当中具有较高的准确性,可作为一项筛选检查。
Objective Dual-source computed tomography angiography （DSCTA） is commonly used in the diagnosis of in- tracranial aneurysm （IA）, but its application to the diagnosis of moyamoya disease with IA is rarely reported. The purpose of this study was to explore the value of DSCTA in detecting IA in patients with moyamoya disease. Methods This study included 32 cases of moyamoya disease diagnosed by both DSCTA and digital subtraction angiography （DSA）. Based on the criteria of DSA, we determined the sensitivity, specificity, positive predictive value and negative predictive value of DSCTA in detecting IA in patients with moyamoya disease. Results DSCTA revealed IA in 13 of the 32 patients with moyamoya disease, including 2 cases of multiple aneurysms, 15 tumors in all, while DSA showed IA in 12 cases, with 13 tumors, located in the circle of Willis. According to the diagnostic criteria of DSA, the sensitivity, specificity, positive predictive value and negative predictive value of DSCTA were 100%, 95.0%, 92.3% and 100%, respectively, in the diagnosis of the 13 IA patients, and 100%, 90.5%, 86.7% and 100%, respectively, in the diagnosis of the 15 tumors. Conclusion DSCTA is highly accurate in the detection of intracranial aneurysm in patients with moyamoya disease, and can be used as a routine screening technique.
出处
《医学研究生学报》
CAS
北大核心
2012年第10期1035-1039,共5页
Journal of Medical Postgraduates
基金
国家973计划基金(2006CB705707)
作者简介
医学硕士研究生
通讯作者：卢光明，E-mail：cjr．1uguangming@vip．163．com
