摘要
目的:研究消痹汤对寻常型银屑病患者血清TGF-β1的影响,探讨该方对TGF-β1干预作用和治疗寻常型银屑病可能的机制或靶点。方法:临床选择银屑病患者40例,随机分为治疗组20例和对照组20例。治疗组内服消痹汤;对照组内服阿维A胶囊。分别于治疗前后早晨8时左右空腹静脉取血4 mL,测定血清TGF-β1水平,观察其变化。结果:消痹汤治疗前后患者血清TGF-β1比较,差异有统计学意义(P<0.05)。结论:消痹汤可明显升高银屑病患者血清TGF-β1水平,从而取得更好的临床疗效。
Objective：To observe the conduct of Xiao Bi Tang decoction group patients with psoriasis vulgaris（blood-heat and wind-dryness pattern in Traditional Chinese Medicine） before and after treatment of serum TGF-β1（transforming growth factor-β1）levels and to explore the side of the TGF-β1 and the intervention of the Treatment of psoriasis vulgaris may be the mechanism or target.Methods：40 cases were selected randomly as the main object of observation,respectively.20 cases in control group were treated with acitretin capsules.20 cases in treatment group were treated with Xiao Bi Tang decoction.before and after treatment at about 800 fasting venous blood 4 mL,serum TGF-β1 then observe changes.Results：Xiao Bi Tang decoction group after treatment of serum TGF-β1 levels were significantly higher than before treatment.Conclusion：＂Xiao Bi Tang＂ can significant increase TGF-β1 levels of patients with psoriasis vulgaris.Xiao Bi Tang is more effective than acitretin capsules in treating patients with psorasis vulgaris.
出处
《中医学报》
CAS
2012年第11期1504-1506,共3页
Acta Chinese Medicine
基金
贵州省科学技术基金项目[编号:(2010)2205]
关键词
寻常型银屑病
消痹汤
血热风燥证
TGF-Β1
psorasis vulgaris
Xiao Bi Tang decoction
blood-heat and wind-dryness pattern
TGF-β1
作者简介
贾敏（1956-），女，回族，河南南阳人，医学学士，主任医师，研究方向：中西医结合治疗皮肤病
通讯作者：贺爱娟（1979-），女，河南南阳人，医学硕士，主治医师。Email：haj79@163．com；Tel：18798769491
