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儿童白癜风患者血清中25-羟维生素D水平的检测 被引量:4

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摘要 目的:观察白癜风患儿体内25-羟维生素D[25-hydroxy vitamin D,25-(OH)D]水平,并探讨其临床意义。方法:取清晨空腹静脉血,采用酶联免疫吸附法(ELISA)检测65例白癜风患儿及111例健康儿童血清25-(OH)D水平。结果:白癜风组患儿血清25-(OH)D平均水平明显低于正常儿童,差异有统计学意义(P<0.01)。65例中37例患儿(占56.9%)血清25-(OH)D水平低于正常值下限(50 nmol/L),25-(OH)D平均水平为(34.92±8.24)nmol/L。健康对照组111例健康儿童中27例(占24.3%)血清25-(OH)D水平低于正常值下限,25-(OH)D平均水平为(42.20±6.14)nmol/L。进展期与稳定期白癜风患儿血清中25-(OH)D平均水平差异无统计学意义(P>0.05)。结论:白癜风患儿维生素D水平低于正常儿童,应引起重视,可能与发病有关。
出处 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2012年第10期1436-1438,共3页 Journal of Nanjing Medical University(Natural Sciences)
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共引文献1090

同被引文献47

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