摘要
目的探讨气管镜辅助治疗COPD合并呼吸衰竭的方法及临床疗效。方法选取我院收治的COPD合并呼吸衰竭患者80例随机分为两组,对照组40名行常规治疗及无创正压通气(NIPPV),实验组40名联合床旁纤维支气管镜吸痰及局部注药,随访2-3周,比较两组患者的临床疗效、血气指标、肺功能指标变化。结果实验组患者的总有效率为95.0%,明显高于对照组的82.5%(P<0.05)。治疗后实验组患者的PaO2、PaCO2、PH等血气指标,用力肺活量(FVC)、用力1 s肺活量(FEV1)、最大呼气流速值(PEF)等肺功能指标均优于对照组(P<0.05)。结论采用气管镜辅助治疗COPD合并呼吸衰竭,可有效改善患者的临床症状及体征,提高临床疗效,值得借鉴。
Objective To study the of clinical effect of bronchoscope in adjuvant treatment of COPD with respiratory failure. Methods In our hospital, 80 COPD patients with respiratory failure were randomly divided into two groups, the control group of 40 cases with conventional therapy and noninvasive positive pressure ventilation （NIPPV）, the experimental group of 40 cases with combined bed- side fiberoptic sputum aspiration and local drug injection. In 2 ~ 3 weeks follow-up, clinical effect, blood gas and pulmonary function changes were compared between two groups. Results After treatment, total effective rate in experimental group （95.0%） was significant higher than that in control group （ 82.5 % ） （ P 〈 O. 05 ）. PaO2, PaCO2, PH and blood gas index, forced vital capacity （ FVC）, forced vital capacity （ 1 s FEV1 ）, peak expiratory flow rate value （ PEF ） and other lung function indices in experimental group were better than those in control group （ P 〈0. 05 ）. Conclusion Using bronchoscope in adjuvant treatment of COPD with respiratory failure can effectively improve the clinical symptoms and signs, improve clinical curative effect, and is worth to be spreaded.
出处
《临床肺科杂志》
2012年第11期1993-1994,共2页
Journal of Clinical Pulmonary Medicine
关键词
纤维支气管镜吸痰
慢性阻塞性肺疾病
呼吸衰竭
bronchofiberscope suctioning
chronic obstructive pulmonary disease
respiratory failure
