摘要
目的:探讨重叠综合征(overlap syndrome,OS)患者和阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome OSAHS)患者的肺功能与睡眠呼吸紊乱之间的特点。方法:观察OSAHS患者61例,其中OS组29例,单纯OSAHS组32例,两组患者均行多导睡眠仪及肺功能检测。比较两组睡眠呼吸紊乱、肺功能指标。结果:睡眠监测指标:两组在平均SaO_2%(MSaO_2)、最长呼吸暂停时间(DBLon)、血氧饱和度低于90%的时间占总记录时间百分比(TS90%)等方面差异有统计学意义(P<0.05)。肺功能指标:两组在FEV1占预计值百分比(FEV_1%)和1秒率(FEV_1/FVC)方面差异有非常显著性意义(P<0.01)。结论:OS患者夜间低氧血症、肺功能下降较单纯OSAHS患者更为明显,及时诊断和合理治疗OS具有重要临床意义。
Objective ：To study the relations between pulmonary function and nocturnal respiratory disorders in the patients with pure obstructive sleep apnea-hypopnea syndrome（OSAHS） and overlap syndrome（OS）.Methods ：Sixty-one subjects who were diagnosed as OSAHS by polysomnography were studied.Their pulmonary functions were measured.The subjects were divided into two groups in relation to the presence of pure OSAHS patients and OS patients.Comparisions were made in pulmonary function, AHI, MSaO2 and TS90% between 32 OSAHS patients and 29 OS patients.Results ：There were significant difference on MSaO2, DBLon, TS90% between OS and OSAHS（P〈0.05）.There were significant difference on FEV1%, FEV1/FVC between OS and OSAHS（P〈0.01）.Conclusion ：More severe night/noctarnal hypoxemia and damaged pulmonary function are present in the patients with OS than pure OSAHS. Prompt diagnosis and appropriate treatment bear great clinical significance for the patients with overlap syndrome.
出处
《中外医学研究》
2012年第26期10-11,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
