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血小板参数与脑梗死、下肢静脉血栓相关性的探讨 被引量:2

Discussion on Correlations between Platelet Parameters and Cerebral Infarction, Low Limb Vein Thrombus
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摘要 目的:探讨血小板计数(PLT)、血小板压积(PCT)、平均血小板体积(MPV)、血小板分布宽度(PDW)及大血小板比率(P-LCR)与脑梗死、下肢静脉血栓的相关性。方法:测定脑梗死组40例、下肢静脉血栓组28例及健康体检者(正常对照组)40例的PLT、PCT、MPV、PDW及P-LCR值,并进行统计分析。结果:(1)脑梗死组MPV、PDW、P-LCR检测结果分别为:11.3±1.1fl、15.1±2.8fl、(34.9±7.9)%,对照组分别为:10.3±0.8fl、12.6±1.6 fl、(27.8±5.4)%,两组比较差异有统计学意义(P<0.01)。(2)下肢静脉血栓组MPV、PDW、P-LCR检测结果分别为11.0±1.1fl、14.6±3.3fl、(33.5±8.2)%,与正常对照组比较差异有统计学意义(P<0.05)。结论:MPV、PDW、P-LCR是脑梗死发生的重要危险因子,也可以作为下肢静脉血栓形成的一个危险因素。 Objective :To discuss the correlations between platelet (PLT),plateletcrit (PCT), mean platelet volume (MPV),platelet distribution width (PDW), platelet-large cell ration (P-LCR) and cerebral infarction and low limb vein thrombus. Methods: The PLT, PCT, MPV, PDW and P-LCR of 40 patients with cerebral infarction, 28 patients with low limb vein thmmbus and 40 adults in the control group were statistically analyzed. Results: MPV, PDW and P-LCR of patients with cerebral infarction were 11.3±1.1fl, 15.1±2.8fl,34.9±7.9%, MPV, PDW and P-LCR of adults in the control group were 10.3±0.8fl, 12.6±1.6 and 27.8±5.4%. There were significant differences between the cerebral infarction group and the control group (P〈0.01). MPV, PDW and P-LCR of patients with low limb vein thrombus were 11.0±1.1fl, 14.6±3.3fl and 33.5±8.2% ,which were also different from the control group (P〈0.05). Conclusion: MPV is the important risk factor of cerebral infarction and it is also the risk factor of low limb vein thrombus.
作者 虞艳梅
出处 《交通医学》 2012年第3期232-233,共2页 Medical Journal of Communications
关键词 脑梗死 下肢静脉血栓 血小板平均体积 血小板分布宽度 大血小板比率 cerebral infarction low limb vein thrombus MPV PDW P-LCR
作者简介 虞艳梅,女,汉族,江苏南通人,生于1974年1月,本科,主管检验师。研究方向:主要从事血液学和临床检验。
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  • 1林果为 沈福民.现代临床流行病学[M].上海:上海医科大学出版社,2004.46-56.
  • 2Claudia St,Llberger,Josef Finsterer.Role of infectious and immune factors in coronary and cerebrovascular arteriosclerosis[J].Clin Diagn Lab Immunol,2002,9(2):207-215.
  • 3Martin JF,Bath PMV,Burr ML.Influence of platelet,size on outcome after myocardical infarction[J].Lancet,1991,338:1409.
  • 4Pizzulli L,Yang A,Martin JF,et al.Changes in platelet size and count in unstable angine compared to stable angine or non-cardiac chest pain[J].Eur Heart J,1998,19(1):80-84.
  • 5REINER A P, KUMAR P M, SCHWARTZ S M, et al. Genetic varitants of platelet glycoprotein receptors and risk of stroke in young women[J]. Stroke, 2000,31 : 1628-1633.
  • 6GRAU A J, RUF A, VOGT A, et al. Increased fraction of circulating activated platelets in acute and previous cerebrovascular ischemia[J]. Thromb Haemost, 1998,80:298-301.
  • 7LEYTIN V, SHAKOOR S, MODY M, et al. Sepsis and endotoxemia generated cytokines do not trigger activation of human platelets [J]. Crit Care Med,2002,30: 2771-2773.
  • 8O' MAI.I,F.Y T, LANGHORNE P, ELTON R A. Platelet size in stroke patients[J]. Stroke, 1995, 26: 995-999.
  • 9KRISTENSEN S D. Megakaryoeytes and atherosclerosis [ J ]. Clin Sci, 1992,82:353-355.
  • 10IMAIZUMI M, ASHIDA K, ISAKA Y, et al. Electron microscopic study of blood platelet in ischemic cerebral vascular disease [ J ]. Jap J Stroke, 1990,12:279-283.

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  • 1韩新巍,陈呈世,段广才,水少峰,管生,马南,王艳丽,吴刚,丁鹏绪.下肢静脉血栓患者血小板参数分析[J].血栓与止血学,2007,13(3):124-125. 被引量:3
  • 2温绍君,周玉杰,刘双,等.肺栓塞:多学科病例分析[M].北京:人民卫生出版社,2012:15.
  • 3朱大年.生理学[M].北京:人民卫生出版社,2013.
  • 4JIN SH,TAE SP,SUN YC,et al.Increased mean platelet volume and mean platelet volume/platelet count ratio in Korean patients with deep vein thrombosis[J].Platelets,2013,24(8):590-593.
  • 5ZEYDIN A,MURAT Z,LEVENT K,et al.Mean platelet volume at admission is a determinant of left ventricular thrombus formation after primary percutaneous coronary intervention for first anterior wall myocardial infarction[J].Acta Cardiol,2014,69(6):603-609.
  • 6JOANNA RM,LIDIA G,EWELINA W,et al.The relationship between mean platelet volume and thrombosis recurrence in patients diagnosed with antiphospholipid syndrome [J].Rheumatol Int,2014,34(11):1599-1605.
  • 7BRAEKHAN SK,MATHIESEN EB.Mean platelet volume is a risk factor for venous thromboembolism : the tromso study,tromso,norway[J].J Thromb Haemost,2010,8(1):157-162.
  • 8MONIKAN J,ANNA C,DARIUSZ P,et al.Incidence and risk factors for central venous catheter -related thrombosis in hematological patients[J].Med Oncol,2014,31(1):772.
  • 9ROSS R.Atherosclerosis: an inflammatory disease[J].N Engl J Med,1999,340(2):115-126.
  • 10VAEGDATU E,GOUNARI E,LAZARIDOU E,et al.Platelet distribution width:a simple,practical and specific marker of activation of coagulation[J].Hippokratia,2010,14(1):28-32.

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