摘要
目的 :采用药物定量脑电图检测观察静脉滴注尼莫通对短暂性脑缺血发作 (TIA)病人脑功能的改善作用。方法 :对 30例TIA病人用静滴尼莫通 5 0ml治疗 ,比较治疗前后定量脑电图主频、θ、δ频段相对功率值的动态变化 ,并设置年龄匹配的对照组 2 5例进行比较。结果 :对照组与治疗组治疗前及治疗后主频、θ、δ相对功率值有显著性差异。治疗组治疗前与对照组比较 ,主频呈现慢波化 (后移 ) ,θ、δ相对功率值明显升高 ,治疗后与治疗前比较主频大部分前移 ,θ、δ相对功率值明显下降。结论 :TIA病人定量脑电图显示慢波化趋势 ,存在明显的脑电生理功能障碍。用定量脑电图的指标可以客观判断尼莫通对TIA病人有明确的疗效。
Objective:To assess improvement effect of intravenous Nimotop on the cerebral function of patients with transient ischemic attack (TIA) by medicine quantitative EEG (qEEG).Methods:Thirty patients with TIA were treated by intravenous Nimotop (50ml). The main frequency band and relative power of θ,δ frequency band of qEEGs before and after treatment were compared with each other and 25 subjects with age matched with the patients were served as control group.Result:There are significant difference in main frequency band relative power of θ,δ frequency as compared with the control group before and after intravenous Nimotop, The main frequency band were slower and θ,δ relative power were higher in patients before intravenous Nimotop than that of control group. The main freqency band were become faster and θ,δ relative power were become lower after the patients were treated by intravenous Nimotop. Conclusion:The qEEG showed brain wave slowing in patients with TIA. Obvious disorders of brain electrophysiological function were existed. Index of qEEG might access the curative effect of intravenous Nimotop on patients with TIA.
关键词
短暂性脑缺血发作
定量脑电图
尼莫通
治疗
Transient ischemic attack
Medicine
Quantitative EEG
Nimotop
Curative effect
