摘要
目的探讨类风湿关节炎(RA)肺间质病变(RA-ILD)的发生率及相关因素。方法对资料完整的352例住院RA患者进行回顾性分析,根据诊断分为有ILD组和无ILD组,比较分析RA-ILD发生的相关因素。结果 2005-12～2007-10住院RA患者ILD的发生率为5.1%。单因素分析相关因素为年龄、血免疫球蛋白G异常及双手X线Ⅲ/Ⅳ级改变。多因素多元逐步Logistich回归分析,相关因素为年龄和血免疫球蛋白G异常。结论类风湿关节炎肺间质病变发生率高,是多种因素共同作用的结果。
Objective To investigate the incidence and correlative factors of rheumatoid arthritis associated interstitial lung disease （RA-ILD）. Methods The complete medical records of 352 in-patient with rheumatoid arthri- tis （RA） were retrospectively analyzed. These in-patients were divided two groups： the first group was patients with RA-ILD（ RA-ILD group） and the second without RA-ILD（ no ILD group）. Correlative clinic factors were analyzed by the comparative method. Results The total incidence rate of RA-ILD was 5.1% in these in-patients with RA from December 2005 to October 2007. Monofactorical analysis showed that the correlative factors included age,the abnor- mal level of immunoglobulin G in serum and tile level ]II/IV damage on hand in X-ray;Muhifactoical analysis indica- ted that the correlative factors were age and the abnormal level of immunoglobulin G in serum. Conclusion The inci- dence rate of RA-1LD is higher, and it is tile results of muhiple factors.
出处
《中国临床新医学》
2012年第8期728-730,共3页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
关键词
类风湿关节炎
肺间质病变
相关因素
Rheumatoid arthritis （R_A）
Interstitial lung disease（ILD）
Correlative factors
作者简介
莫轶（1973-），女，医学硕士，主治医师，研究方向：风湿免疫学。E—mail：moyi418@126．com
