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肢端肥大症药物治疗新进展 被引量:2

Research progress of medication treatment for acromegaly
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摘要 肢端肥大症(acromegaly)是由于生长激素(GH)持久过度分泌所引起的一种内分泌代谢疾病。尽管引起肢端肥大症的垂体瘤几乎都是良性肿瘤,但是由于GH和胰岛素样生长因子-1(IGF-1)升高,可以导致心血管系统、呼吸系统、内分泌和代谢的一系列异常改变。最新的荟萃分析结果显示,肢端肥大症患者的标化死亡率(SMR)是1.72(95%CI1.62-1.83),其全因死亡率与正常人群相比增加了32%。
作者 段炼 顾锋
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2012年第8期631-634,共4页 Chinese Journal of Practical Internal Medicine
关键词 肢端肥大症 生长抑素类似物 多巴胺受体激动剂 生长激素受体拮抗剂 acromegaly somatostatin analog dopamine agonist growth hormone receptor antagonist
作者简介 通讯作者:顾锋,电子信箱:gufengl025@yahoo.com.cn
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