摘要
A simple and efficient procedure for the preparation of silica-bound N-propyl triethylenetetramine sulfamic acid(SBPTETSA) by the reaction of silica-bound N-propyl triethylenetetramine(SBPTET) with chlorosulfonic acid in chloroform is described.Silica-bound N-propyl triethylenetetramine sulfamic acid was employed as a recyclable catalyst for the synthesis of 2-amino-4,6-diarylnicotinonitriles from the multi-component reaction of an acetophenone derivative,an aromatic aldehyde,malononitrile,and ammonium acetate under solvent-free conditions at 100 °C.The heterogeneous catalyst was recycled for five consecutive runs in the optimized multi-component reaction of 4-chloroacetophenone,4-chloroenzaldehyde,malononitrile,and ammonium acetate without significant loses to its catalytic activity.
A simple and efficient procedure for the preparation of silica-bound N-propyl triethylenetetramine sulfamic acid（SBPTETSA） by the reaction of silica-bound N-propyl triethylenetetramine（SBPTET） with chlorosulfonic acid in chloroform is described.Silica-bound N-propyl triethylenetetramine sulfamic acid was employed as a recyclable catalyst for the synthesis of 2-amino-4,6-diarylnicotinonitriles from the multi-component reaction of an acetophenone derivative,an aromatic aldehyde,malononitrile,and ammonium acetate under solvent-free conditions at 100 °C.The heterogeneous catalyst was recycled for five consecutive runs in the optimized multi-component reaction of 4-chloroacetophenone,4-chloroenzaldehyde,malononitrile,and ammonium acetate without significant loses to its catalytic activity.
出处
《催化学报》
SCIE
EI
CAS
CSCD
北大核心
2012年第8期1312-1317,共6页
基金
supported by Persian Gulf University Research Council(PGU/FS/6-1/1390/705)
关键词
三乙烯四胺
固体酸催化剂
氨基磺酸
氧化硅
可回收
丙基
合成
苯乙酮衍生物
silica-bonded N-propyl triethylenetetramine sulfamic acid 2-amino-4,6-diarylnicotinonitrile pyridine aldehyde solvent-free
