摘要
目的:了解流动人口密集地区妇科宫颈人乳头瘤病毒感染的现状。方法:采用记事簿及表格登记方式对妇科门诊每阶段HPV检测人数、结果呈阳性(高危及低危亚型)人数和每位感染者的基本资料、HPV亚型类别等进行登记,特别病例行电话回访。结果:在2 674例检测对象中呈阳性者有500例占18.7%,其中单亚型感染者372例占13.91%,多亚型感染者128例占4.79%;在所有受调查者中共检出高危HPV毒株517人次(位于前五位的依次是HPV16、HPV52、HPV58、HPV68、HPV18)及检出低危HPV毒株190人次(依次分别为HPV43、HPV11、HPV6、HPV42、HPV44);在128例多亚型感染者中检出2种亚型的有91例占71.09%,检出3项亚型的有23例占17.97%,检出4项亚型的有6例占4.69%,检出5项及以上亚型的有8例占6.25%,其中年龄段在17～29岁的患者77例占60.15%,30～49岁的51例占39.85%。结论:流动人口密集地区宫颈HPV感染以高危型的HPV16.52.58及低危型的HPV43、11、6为主,复杂严重的多亚型混合感染比例大且高度集中于17～29岁年龄段患者,潜在极大的宫颈癌年轻化发病风险。
Objective To understand the flow gynecological cervical human papillomavirus infection status in densely populated areas and related factors. Method Noted and table for each stage of the gynecological clinic number of HPV testing,positive results （number of high- risk and low- risk subtypes）, basic information of each infected person infected by HPV types, Special cases underwent telephone interviews. Results Positive persons accounted for 500 cases （ 18.7 % ）, in which a single subtype infection 13.91% of 372 eases, 128 ea- ses of the multi -subtype infection accounted for 4.79% of 2674 eases of detected objects;In all respondents were detected with high risk HPV strain 517 times （ Located in the top five was HPV16,52,58,68,18 ） and detected with low - risk HPV strain 190 times （ Respective- ly HPV43,11,6,42,44） ;In 128 patients with infected in the detection of 2 subtypes of 91cases 71.09%, positive 3 subtypes of 23 cases was 17.97% ,positive 4 subtypes of 6 eases was 4.69% ,positive 5 and above subtypes of 8 cases was 6. 25% ,The age in 17 -29 year old patients had 77 eases was 60. 15%, the age in 30 -49year old patients 51cases 39. 85.31%. Conclusion Temporarily living in densely populated areas of Cervical HPV infection with high -risk types of HPV16,52,58 and low risk type HPV43. 11.6 ,the most common ,com- plicated severe with mixed infection ratio is large and highly concentrated in the 17 -29 years old age patients, potential huge risk of cervi- cal eaneer in young.
出处
《吉林医学》
CAS
2012年第22期4810-4812,共3页
Jilin Medical Journal
基金
广东省东莞市科研基金资助项目(2010105150115)
关键词
宫颈
人乳头瘤病毒
混合感染
Cervical
Human papillomavirus
Mixed - nfection
