摘要
A catalytic addition of amine N H bonds to carbodiimides using aluminum chloride as a Lewis acid catalyst is developed.The reaction proceeds under mild conditions without solvent to afford a series of substituted guanidines in good to excellent yields using a wide range of amines as substrates.Evidence of the proposed mechanism is provided by in situ infrared spectroscopy.
A catalytic addition of amine N-H bonds to carbodiimides using aluminum chloride as a Lewis acid catalyst is developed. The reaction proceeds under mild conditions without solvent to afford a series of substituted guanidines in good to excellent yields using a wide range of amines as substrates. Evidence of the proposed mechanism is provided by in situ infrared spectroscopy.
基金
supported by the National Natural Science Foundation of China (20972107,20872106)
the Department of National Education PhD Foundation
the Priority Academic Program Development of Jiangsu Higher Education Institutions
作者简介
Corresponding authors:XU Fan,email:xufan@suda.edu.cn;Corresponding authors:SHEN Qi,email:qshen@suda.edu.cn.
