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抗甲状腺球蛋白抗体与抗甲状腺过氧化物酶抗体在甲状腺功能异常诊断中的应用 被引量:14

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摘要 目的观察抗甲状腺球蛋白抗体(A-TG)、抗甲状腺过氧化物酶抗体(A-TPO)与甲状腺功能异常的关系,探讨其在临床诊断中的应用价值。方法以电化学发光法检测140例甲状腺功能异常的患者(按病情分为亚临床甲亢组、临床甲亢组、亚临床甲减组与临床甲减组)和226例甲状腺功能正常者(对照组)的血清A-TG与A-TPO的水平。结果亚临床甲亢组、临床甲亢组、亚临床甲减组与临床甲减组的A-TG水平、A-TPO水平、A-TG、A-TPO阳性率均明显高于对照组,差异均有显著意义(P<0.01)。结论血清A-TG和A-TPO检测异常与甲状腺功能损伤间存在密切关系。血清A-TG和A-TPO可作为甲状腺功能异常的辅助诊断指标。
出处 《临床和实验医学杂志》 2012年第13期1048-1049,共2页 Journal of Clinical and Experimental Medicine
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