摘要
目的观察复方黄芩含漱液与康复新液联用以减轻鼻咽癌同期放化疗中急性放射性口咽炎的临床近期疗效,并总结护理经验。方法收集中山大学附属江门医院局部晚期鼻咽癌患者101例,随机分为观察组52例和对照组49例,两组均行同期放化疗。观察组予复方黄芩含漱液含漱与康复新液含服联用,同时实施心理护理、饮食护理、口腔护理及功能锻炼等相关护理措施,对照组应用朵贝氏液含漱,实施常规护理,两组给药均从放化疗第一日开始至放疗结束。观察并比较两组患者Ⅲ度以上急性放射性口咽炎反应发生率及出现Ⅲ度以上急性口咽炎发生的时间。结果观察组Ⅲ度以上急性口咽炎发生率低于对照组,两组Ⅲ度以上口咽炎发生率分别为28.85%、61.22%(P<0.001),差别有统计学意义;观察组和对照组放疗14 d后Ⅲ度以上急性口咽炎反应放射率分别为80%、43.33%(P<0.05),差别有统计学意义,观察组Ⅲ度以上急性口咽炎反应放射率发生时间较对照组推迟。结论复方黄芩含漱液与康复新液联用,治疗过程中加强相关护理措施,能降低鼻咽癌同期放化疗中Ⅲ度以上急性放射性口咽炎反应并推迟重度放射性口咽炎发生的时间,从而提高了同期放化疗的耐受性及治疗的依从性,使放化疗顺利进行,近期疗效满意,值得临床推广应用。
Objective To investigate the clinical effect of rinsing the mouth with fufanghuanqinhansuye and Kangfuxin in the prevention and treatment of concurrent chemoradiotherapy related acute stomatitis for patients with local advanced nasopharyngeal carcinoma（NPC）.Methods 101 patients with NPC accepted concurrent chemoradiotherapy were randomly divided into experimental group（52 cases） and control group（49 cases）.The two groups of patients were given concurrent chemoradiotherapy,while the experimental group patients were given the fufanghuanqinhansuye and Kangfuxin to rinse the mouth and added to the mental care,diet care,oral care and functional exercises etc,while the control group was given the Compound Borax Solution and routine nursing care from beginning to ending of treatment.The rate and time of Ⅲ degrees or above acute stomatitis were compared between the two groups.Results The rates of Ⅲ degrees or above acute stomatitis were 28.85% in the experimental group（Group A） and 61.22% in the control group（Group B）,respectively in the both groups（P0.001）;the time of Ⅲ degrees or above acute stomatitis was 80.0% in Group A,while 43.33 % in Group B（P0.05）.Conclusion The rate and time of Ⅲ degrees or above acute stomatitis was reduced and the time was postponed by rinsing the mouth with fufanghuanqinhansuye and Kangfuxin for patients with NPC.The treatment compliance was significantly improved for the patients given concurrent chemoradiotherapy;it should be emphasized and put into practice widely.
出处
《中华全科医学》
2012年第7期1152-1153,共2页
Chinese Journal of General Practice
关键词
同期放化疗
口咽炎
复方黄芩含漱液
康复新液
护理
Concurrent chemoradiotherapy
Stomatitis
Fufanghuanqinhansuye
Comfortable care
作者简介
通讯作者：邓金笑，电子信箱：ldzhao28@sina．com
