摘要
以大脑网络研究为例,详细介绍了大脑网络的构建、结构网络、功能网络以及结构与功能的联系等方面的研究进展.基于复杂网络理论,对大脑结构网络和功能网络的分析得到很多重要的拓扑性质,如"小世界"、"无标度"、模块化以及核心脑区的分布等;另外发现认知功能、神经精神疾病与大脑结构和功能网络的拓扑结构变化或异常有关;总结了国内外在此领域的研究成果,提出了大脑网络研究工作面临的挑战,并展望了将来发展方向.
Progresses in studies of complex networks and its applications in brain network were retrostcted, including the research on topology structure features of anatomical and functional brain networks,as well as on the relationship between brain structures and functions. Based on complex networks theory, some inerrant topology features of anatomical and functional brain networks were reported, such as small world,scale free,modular and hub regions; then some new findings were presented about the relationship between cognitive function and neuropsychiatry disorder with abnormalities in functional connectivity and changes in topological structure changes. Several challenges and key issues that should be addressed in the future were further raised.
出处
《上海理工大学学报》
CAS
北大核心
2012年第2期138-153,共16页
Journal of University of Shanghai For Science and Technology
基金
国家自然科学基金资助项目(10875011
11075016)
教育部博士点基金资助项目(20100003110007)
北京师范大学自主科研基金创新群体资助项目(2010-001)
北京市优秀人才培养资助项目(2010D005009000009)
北京物资学院青年科研基金资助项目(2010XJQN044)
关键词
复杂网络
大脑网络
功能连接
结构连接
小世界
无标度
complex networks
brain networks
functional connectivity
anatomical conectivity
small world
scale free
作者简介
张方风(1979-),女,讲师,研究方向:复杂网络建模与仿真、认知神经科学与脑科学中的数据挖掘与建模等.E-mail:zzfflora@163.com
郑志刚(联系人),男,教授,研究方向:统计物理、非线性科学.E-mail:zgzheng@bnu.edu.cn