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血清IL-8及CRP与川崎病冠脉损害的相关性研究 被引量:2

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摘要 目的探讨血清C反应蛋白(CRP)和IL-8与川崎病患儿并发冠脉损害的相关性及临床意义。方法分别检测38例川崎病患儿及40例健康儿童血清CRP、IL-8的水平,观察上述指标在两组中的差异,并观察其在川崎病并发冠脉损害患儿中是否存在差异性升高。结果川崎病患儿血清CRP和IL-8的水平显著高于正常对照组(P<0.05),在并发冠脉损害的患者中,血清CRP水平明显高于未并发冠脉损害组患儿,具有统计学差异(P<0.05),而血清IL-8在有无并发冠脉损害两组中不存在差异性(P>0.05)。结论 CRP和IL-8参与川崎病的发展,血清CRP与患儿并发冠脉损害关系密切。
作者 许晓哲
出处 《中国现代药物应用》 2012年第8期30-31,共2页 Chinese Journal of Modern Drug Application
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参考文献6

  • 1梁翊常.川崎病的冠状动脉损伤[J].中国实用儿科杂志,1999,14(3):132-134. 被引量:114
  • 2Rowley A H,Shulman S T.Kawasaki disease.In:Behrman R E,Kliegma R M,Arivin A M,J eds.Nelson textbook of pediatrics.16th ed.Philadelphia:W.B.Saunders,2000:725-727.
  • 3吴瑞萍,胡亚美,江载芳.实用儿科学.6版.北京:人民卫生出版社,2002:687-694.
  • 4Gupa M,Noel G T,Schaefer M,et al.Cytokine modulation with immune gamma-globulin in peripheral blood of normal children and its implications in Kawasaki disease treatment.J Clin Immunol,2001,21:193-19.
  • 5Asano T,Ogawa S.Expression of IL-8in Kawasaki disease.Clin Exp Immunol,2000,122:514-51.
  • 6张永兰,杜忠东.小儿川崎病冠状动脉损伤的危险因素[J].中国实用儿科杂志,2006,21(10):742-744. 被引量:48

二级参考文献12

  • 1Takahashi K,Oharaseki T,Naoe S,et al.Neutrophilic involvement in the damage to coronary arteries in acute stage of Kawasaki disease[J].Pediatr Int.,2005,47 (3):305-310.
  • 2Singh-Grewal D,Wong M,Isaacs D.Diagnosis,treatment and outcome of Kawasaki disease in an Australian tertiary setting:a review of three years experience[J].J Paediatr Child Health,2005,41 (10):495-499.
  • 3Kawasaki T.Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children (Japanese)[J].Japan J Allergy,1967,16:178-122.
  • 4Du ZD,Zhang T,Liang L,et al.Epidemiologic picture of Kawasaki disease in Beijing from 1995 through 1999[J].Pediatr Infect Dis J,2002,21 (2):103-107.
  • 5Falcini F,Cimaz R,Calabri GB,et al.Kawasaki disease in northem Italy:a multicenter retrospective study of 250 patients.Clin Exp Rheumatol[J].2002 May-Jun,20(3):421-426.
  • 6Zhang T,Yanagawa H,Oki I,et al.Factors related to cardiac sequelae of Kawasaki disease[J].Eur J Pediatr,1999,158:694-697.
  • 7Salice P,Pietrogrande MC,Barbier P,et al.Cardiovascular abnormalities in Kawasaki disease:an Italian prospective study (Italian)[J].Cardiologia,1998,43 (12):1367-1374.
  • 8Laupland KB,Dele DH (1999).Epidemiology,etiology,and management of Kawasaki disease:state of the art[J].Pediatr Cardiol,20:177-183.
  • 9Koyanagi H,Nakamura Y,Yanagawa H.Lower level of serum potassium and higher level of C-reactive protein as an independent risk factor for giant aneurysms in Kawasaki disease[J].Acta Paediatr,1998,87:32-36.
  • 10Mori M,Imagawa T,Yasui K,et al.Predictors of coronary artery lesions after intravenous gamma-globulin treatment in Kawasaki disease[J].J Pediatr,2000,137(2):177-180.

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