摘要
目的:探讨了原发性高血压肾病患者血清Hcy、血浆vWF和D-D水平的变化及临床意义。方法:应用免疫化学法和酶联法对38例原发性高血压肾病患者进行了血清Hcy、血浆vWF和D-D检测,并与35例正常健康人作比较。结果:原发性高血压肾病患者血清Hcy、血浆vWF和D-D水平非常显著地高于正常人组(P<0.01)且血清Hcy水平与血浆vWF、D-D水平呈正相关(r=0.2612、0.6823,P<0.01)。结论:原发性高血压肾病患者的发生发展与血清Hcy、血浆vWF和D-D水平密切相关。
Objective To explore the clinical essential hypertension significance of changes on serun. Hey, vWF and D-D levels in patients with nephropathy. Methods Serun Hey（with immunoehemistry method） serun vWF, D-D （with ELISA）levels were meas- ured in 38 patients with essential hyper tension complicated with nephropathy as well as in 35 normal controls. Results Serun Hey, vWF and D-D levels were significantly higher than those in eentrols （ P 〈 0.01 ）. Serum Hey levels were significantly positively eerrelat- ed with the vWF, D-D levels （ r = 0.5612, 0. 6823, P 〈 0.01 ）. Conclusion Serun Hey, vWF and D-D levels increased distinctly in patients with essential hypertensin complicated with nephropathy and were mutually postively correlated.
出处
《放射免疫学杂志》
CAS
2012年第2期205-207,共3页
Journal of Radioimmanology
关键词
原发性高血压肾病
同型半胱氨酸
血管性血友病因子
D-二聚体
essential hypertension complicated with nephropathy, homocysteine （Hcy）, von WiUebrand factor（ vWF）, D-Dimer（D-D）
