摘要
目的探寻提高肾气虚型青春期无排卵功能失调性子宫出血临床疗效的治疗方法。方法将60例肾气虚型青春期无排卵功能失调性子宫出血患者随机分为治疗组和对照组,每组各30例。开始时两组均采用雌激素和孕激素止血,下一周期开始,治疗组予中药补肾调周配合小剂量雌激素和孕激素治疗;对照组予阿胶当归口服液和右归胶囊配合小剂量雌激素和孕激素治疗。两组连续治疗3个月经周期。观察并比较两组综合疗效、主要诊断指标(包括月经情况和基础体温)疗效和肾气虚证候疗效。结果治疗组综合疗效、主要诊断指标疗效和肾气虚证候疗效显著优于对照组(P<0.05);在第3疗程末,治疗组疾病分级量化积分和中医证候积分显著低于对照组(P<0.05,或P<0.01);两组复发率比较,差异无统计学意义。结论中药补肾调周法配合小剂量雌激素和孕激素治疗青春期无排卵功能失调性子宫出血能明显提高疗效。
Objective To explore a treatment strategy for improving adolescent anovulatory dysfunctional uterine bleeding complicated with kidney-qi deficiency syndrome. Methods Sixty patients with adolescent anovulatory disfunctional uterine bleeding complicated with kidney-qi deficiency syndrome were averagely randomized into treatment group and control group. At the beginning, patients in both groups were trea- ted with estrogen and progestogen to stop bleeding. From the next menstrual cycle, patients in the treat- ment group were treated with traditional Chinese medicine for tonifying kidney and adjusting menstrual cycle combined with low-dose estrogen and progestogen; while patients in the control group were treated with Chinese patent medicines （including E Jiao Danggui Oral Liquid and You Gui Capsules） and low-dose estrogen and progestogen. Patients in both groups were continuously treated for three menstrual cycles. The composite therapeutic effects, the therapeutic effects of main diagnostic indicators （including menstru- al conditions and basal body temperature）, and the therapeutic effects of kidney-qi deficiency syndrome were observed and compared between the two groups. Results The composite therapeutic effects, the therapeutic effects of main diagnostic indicators, and the therapeutic effects of kidney-qi deficiency syndrome in the treatment group were significantly better than those in the control group （P〈0.05）. At the end of 3rd treatment course, the scores of disease grading and traditional Chinese medicine syndrome in the treatment group were obviously lower than those in the control group. There was no significant difference in the recurrence rate between the two groups. Conclusion The therapy of tonifying kidney and adjusting menstrual cycle, if combined with low-dose sex hormones, can improve the therapeutic effects of adolescent anovulatory dysfunctional uterine bleeding complicated with kidney-qi deficiency syndrome.
出处
《安徽中医学院学报》
CAS
2012年第2期20-23,共4页
Journal of Anhui Traditional Chinese Medical College
基金
安徽中医学院临床科学研究基金项目(2009LC1-019A)
关键词
功能失调性子宫出血
无排卵
青春期
肾气虚证
补肾调周法
dysfunctional uterine bleeding
anovulation
adolescence
kidney deficiency syndrome~ tonify-ing kidney-qi and adjusting menstrual cycle
作者简介
作者简介：程红（1970-），女，副主任医师
