摘要
比较了由诺卜醇氢化合成氢化诺卜醇的两种方法:钠和正丁醇或异戊醇的化学还原法、镍催化的加压氢化法。气相色谱分析表明:用两种方法合成氢化诺卜醇时均有两种顺反异构体生成,且以顺式异构体为主;催化加压时,产物中的反式异构体仅占5%以下,用化学还原法时,反式异构体在产物中可达20%。从几方面考虑,合成cis-氢化诺卜醇应采用诺卜醇催化氢化法。
Two synthetic methods of hydronopol from nopol were compared in this article. The two methods were chemical reduction with sodium and n-butanol or isoamyl alcohol, and pressure hydrogenation catalyzed by Raney Ni respectively. GC analysis showed that both methods would give cisand trans-isomer, and the main product was cis-isomer. Less than 5% of the product of pressure hydrogenation was trans-isomer, while near 20% trans isomer was obtained in chemical reduction method. Taking all factors into consideration, pressure hydrogenation is the appropriate method to synthesize cishydronopol.
出处
《化学世界》
CAS
CSCD
北大核心
2012年第3期163-164,168,175,共4页
Chemical World
基金
国家自然科学基金项目(30860223
31060101)
教育部留学回国人员科研启动基金项目([2010]1561)
江西省青年科学家(井冈之星)培养对象计划资助项目
关键词
诺卜醇
氢化诺卜醇
化学还原
催化氢化
合成
nopol
hydronopol
chemical reduction
catalytic hydrogenation
synthesis
作者简介
赵玲华(1987-),女,江西彭泽人,硕士生,主要从事林产化工的研究;王宗德,E-mail:zongdewang@163.com.
