摘要
目的:探讨布地奈德吸入治疗儿童咳嗽变异性哮喘的临床疗效和安全性。方法:选取咳嗽变异性哮喘患儿60例,随机分为对照组及布地奈德治疗组,比较两组患者咳嗽缓解及消失时间、PEF达预测值的百分比、血清IgE水平及外周血嗜酸性粒细胞计数的变化、咳嗽恶化次数和典型哮喘发生率及复发率。结果:治疗组与对照组比较,临床有效率及PEF达预测值的百分比明显提高、IgE水平及外周嗜酸性粒细胞计数水平、咳嗽缓解时间及咳嗽消失时间、升高、咳嗽症状恶化次数、典型哮喘转化数、复发率均减少,差异具有统计学意义(P<0.05)。结论:布地奈德雾化吸入能够迅速缓解CVA的症状,临床治疗效果确切,值得临床应用。
Objective： To explore the clinical efficacy and safety of budesonide inhalation on children with CVA.Method： Choose 60 children with CVA,All the patients were divided randomly into two groups： the treatment group treated with budesonide,but the control group wasn＇t.Compared the time of cough relief and the disappearance,the percentage of PEF in predicted value,IgE level and eosinophil count changes,treatment,cough worse times,the incidence of typical asthma and recurrence rate in the two groups.Result： Compared the control,the clinical efficiency and the percentage of PEF in predicted significantly improved,IgE level and peripheral eosinophil count,the time of cough relief and disappearance,cough worse times,the incidence of typical asthma and recurrence rate were reduced,There＇s significant difference（P0.05）.Conclusion： Budesonide inhalation can quickly relieve the symptoms of CVA,has exact clinical treatment,it is worthy of clinical application.
出处
《河北医学》
CAS
2012年第3期360-363,共4页
Hebei Medicine
