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宫腔镜治疗子宫内膜息肉及术后复发的预防 被引量:48

The hysteroscopic treatment of endometrial polyps and prevention of polyps recurrence
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摘要 目的探讨子宫内膜息肉的宫腔镜手术治疗及术后应用孕激素预防复发的效果。方法选择定州市人民医院2005年8月~2009年8月行宫腔镜诊治的子宫内膜息肉86例患者,术后分为激素治疗组和观察组,激素治疗组术后给予安宫黄体酮周期性治疗3个月,观察子宫内膜息肉复发及妊娠情况。结果 86例患者中,宫腔镜检查多发性子宫内膜息肉56例,单发性子宫内膜息肉32例;激素治疗组术后2年,复发率为2.3%,观察组复发率为13.9%,两组比较,差异有显著性(P<0.05)。32例有生育要求的患者中,术后2年23例自然妊娠,妊娠率为71.9%,但激素治疗组妊娠率(70.6%,12/17)和观察组(73.3%,11/15)比较,差异无显著性(P>0.05)。结论子宫内膜息肉患者行宫腔镜诊断及治疗效果明确,术后应用孕激素治疗可能有助于预防子宫内膜息肉的复发。 [Objective] To evaluate the clinical effectiveness of hysteroscopy surgery combined with progestin taken for the treatment of endometrial polyps.[Methods] 86 patients with endomet rail polyps who underwent hysteroscopic polypectomy were recruited.According to progestin taken or not,patients were randomly divided into two groups:those treated with progestin for 3 months were in progestin group,others were only under follow up(control group).All patients were followed up for 2 years.[Results] Among the 86 patients,56 patients were diagnosed of multiple endometrial polyps,and the other 32 patients were diagnosed of single endometrial polyp.After 2 years follow-up,the recurrent rate was 2.3% in progestin group and 13.9% in control group(P 0.05).Among the 32 patients who had fertility requirement,23 were pregnant naturally with the71.9% of pregnancy rate.The pregnancy rate had no significant difference between the two groups(P 0.05).[Conclusions] Hysteroscopy is an effective method for the diagnosis and treatment of endometrial polyps.Progestin treatment after endometrial polypectomy can decrease the recurrence rate.
出处 《中国内镜杂志》 CSCD 北大核心 2012年第1期78-80,共3页 China Journal of Endoscopy
关键词 子宫内膜息肉 宫腔镜 复发 孕激素 endometrial polyps hysteroscopy recurrence progestin
作者简介 [通信作者]孟丽,E-mail:mengliabc@126.com,电话:0312—2330138
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参考文献12

  • 1郭春,黄薇.子宫内膜息肉与不孕[J].实用妇产科杂志,2009,25(9):526-528. 被引量:40
  • 2W ANG J H,ZH AO J,LIN J.Opportunities and risk factors for prem alignant and m alignant transform ation of endom et rial polyps:m anagem ent strategies[J].J M inim Invasive Gynecol,2010,17(6):53-58.
  • 3RAH IM I S,M ARANI C,RENZI C,et al.Endom et rial polyps and the risk of atypical hyperplasia on biopsies of unrem arkable endom et rium:a study on694patient s wit h benign endom etrial polyps[J].Int J Gynecol Pathol,2009,28(7):522-528.
  • 4李燕,丁岩.宫腔镜电切术联合药物治疗子宫内膜息肉的效果观察[J].新疆医科大学学报,2008,31(1):68-70. 被引量:26
  • 5PENG X,LI T,XIA E,et al.A com parison of oest rogen receptor and progesterone receptor expression in endom et rial polyps and endom et rium of prem enopausal wom en[J].Obstet Gynecol,2009,29(2):340-346.
  • 6KOM M OSS F,KARCK U,PRM PELER H,et al.Steroid receptor expression in endom et ria from wom en treated wit h tam oxifen[J].Gynecol Oncol,1998,70(4):188-191.
  • 7KIM M R,KIM YA,JO M Y,et al.H igh f requency of endom et rial polyps in endom et riosis[J].Am Assoc Gynecol Laparosc,2003,10(5):46-48.
  • 8BOUDA J,H RADECKY L,ROKYTA Z.H ysteroscopic polypectom y versus fractionated curettage in the treatm ent of corporal polyps-recurrence of corporal polyps[J].Ceska Gynekol,2000,65(6):147-151.
  • 9SAVELLI L,DELOCA P,SANTINI D,et al.H ystopat hologic features and risk factors for benignity hyperplasia and cancer inendom etrial polyps[J].J Am Assoc Gynecol Laparosc,2003,188(3):927-931.
  • 10GARDNER FJ,KONJIE JC,BELL SC,et al.Prevention of tam ox-ifen induced endom etrial polyps using a levonorgestrel releasing intrauterine system long-term follow-up of a random ised control trial[J].Gynecol Oncol,2009,114(7):452-456.

二级参考文献23

  • 1叶云,吴嘉齐,吴日然,张旭宾.宫腔镜下不同方式治疗子宫内膜息肉不孕患者的临床疗效分析[J].中国内镜杂志,2006,12(4):426-428. 被引量:41
  • 2Hinckley MD, Milki AA. 1000 office-based hysteroscopies prior to in vitro fertilization: feasibility and findings [J].J Soc Laparo Sur, 2004,8 (2) : 103 - 107.
  • 3De Placido G, Clarizia R, Cadente C, et al. Compliance and diagnostic efficacy of mini-hysteroscopy versus traditional hysteroscopy in infertilityinvestigation [ J ]. gut J Obstet Gynecol Reprod Biol, 2007,135 ( 1 ) : 83 - 87.
  • 4Tiufekchieva E. Hysteroscopy in women with reproductive problems [J]. Akusherstvo I Ginekologiia, 2006,45(6) :39 - 44.
  • 5Shokeir TA, Shalan HM, El-Shafei MM. Significance of endometrial polyps detected hysteroscopically in eumenorrheic infertile women [ J]. J Obstet Gynaecol Res,2004,30(2) :84 - 89.
  • 6Yonaihara A, Yorimitsu T, Motoyama H, et al. Location of endometrial polyp and pregnancy rate in infertility patients [J]. Fertil Steril,2006,90 (1):180- 182.
  • 7Isikoglu M, Berkkanoglu M, Senturk Z, et al. Endometrial polyps smaller than 1.5 cm do not affect ICSI outcome [J]. Reprod Biomed Online, 2006,12(2) : 199 - 204.
  • 8Riehlin SS, Ramachandran S,Shanti A, et al. Glyeodelin levels in uterine flushings and in plasma of patients with leiomyomas and polyps: implications for implantation [J]. Hum Reprod,2002,17(10) :2742 - 2747.
  • 9Gebauer G, Hafner A, Siebzehrubl E, et al.Role of hysteroscopy in detection and extraction of endometrial polyps: results of a prospective study [J]. Am J Obstet Gynecol,2001,184(2) :59 - 63.
  • 10Femandez-Parra J, Oliver AR, Criado SL, et al.Hysterosoapie evaluation of endometrial polyps [J], hat J Oynecol Obstet,2006,95(2): 144- 148.

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