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大剂量沐舒坦治疗急性胸部损伤合并肺部感染的疗效分析 被引量:6

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摘要 目的探讨急性胸部损伤合并肺部感染的治疗方法。方法急性胸部损伤合并肺部感染患者108例,随机分为两组,均给予病因治疗和抗感染、液体管理、呼吸机辅助呼吸、加强营养等治疗,实验组同时给予沐舒坦900~1000mg/d持续24h静脉泵入;对照组给予常规小剂量沐舒坦30mg,每8小时1次静脉注射。结果实验组54例患者中感染得到控制49例,感染控制时间平均为(4.5±2.2)d;对照组41例感染得到控制,感染控制时间平均为(7.3±2.2)d,差异有统计学意义(t=8.074,P=0.041)。实验组肺部感染控制率显著高于对照组[90.70%(49/54)与75.93%(41/54),x2=7.471,P=0.035]。结论临床应用大剂量沐舒坦对急性胸部损伤合并肺部感染的预防、治疗和转归具有显著疗效。
作者 许红飞
出处 《中国综合临床》 2012年第3期265-266,共2页 Clinical Medicine of China
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