摘要
目的探讨心肌肌钙蛋白I（cTnI）？超敏C-反应蛋白（hs-CRP）和血乳酸的动态变化在病毒性心肌炎（VMC）诊断中的意义。方法回顾性分析急性病毒性心肌炎患者（VMC组，n=54）和急性上呼吸道感染（上感）患者（上感组，n=34）共88例，动态监测两组cTnI、hs—CRP和血乳酸水平，并对比VMC轻症患者（n=39）与重症患者（n=15）的c咖水平。结果VMC组人院24h内所测得的cTnI水平[（0．59±0．10）ng／L]较上感组[（0．10±0．08）ng／L]明显升高（t=2．79，P〈0．05），其血乳酸（t=2．71，P〈0．05）及hs．CRP水平（t=2．48，P〈0．05）在不同时段也有升高的表现。结论cTnI对诊断病毒性心肌炎有重要的意义，其水平高低与患者病情严重程度相关，hs—CRP及血乳酸与病毒性心肌炎的炎症损伤也有一定相关性。
Objective To explore the diagnostic and predictive value of tropenin I,lactic acid and hypersen-sitive C-reactive protein（hs-CRP） in viral myocarditis. Methods Troponin I ,hs-CRP,lactic acid blood levels in dif- ferent time were measured in 88 patients with acute viral myocarditis （54 cases） or acute upper respiratory infectious （34 cases）. Troponin I level in patients with severe 39 cases and mild VMC 15 cases were compared. Results Troponin I level of VMC group was （0.59 ± 0.10） ng/L, and significantly higher than that of acute upper respiratory infection group [ （0.10±0.08 ） ng/L ] （ t = 2.79, P 〈 0.05 ）. And higher lactic acid and hs-CRP level were observed at different period （ t = 2.71,2.48, all P 〈 0.05 ）. Conclusion Troponin I could help diagnose VMC predict the severity of myocarditis to some extent. Lactic acid and hs-CRP could also reflect imflammation injury of VMC.
出处
《中国基层医药》
CAS
2012年第1期5-6,共2页
Chinese Journal of Primary Medicine and Pharmacy
基金
广东省深圳市2011年科技计划项目（201103082）
