摘要
目的观察补中益气汤对不同生理状态小鼠胃肠运动的影响和抗炎作用。方法通过活性炭小肠推进率试验,观察该方对正常小鼠和番泻叶致泻小鼠的药理作用;通过二甲苯耳廓致炎试验,观察该方的抗炎作用。结果补中益气汤低、中、高剂量均能增加正常小鼠胃肠蠕动;对番泻叶致泻后的小鼠,低、中剂量能减慢小鼠胃肠蠕动,高浓度反而加快小鼠胃肠蠕动;补中益气汤各剂量不同程度地减轻二甲苯所致的耳廓肿胀。结论补中益气汤对小鼠胃肠运动有双向调节作用,对二甲苯致小鼠耳廓肿胀有抗炎作用。
Objective To investigate the influence on gastrointestinal peristalsis and anti-inflammatory effects of Buzhongyiqi decoction in differ-functional status mice.Methods To observe effects of different dosage Buzhongyiqi decoction on assay of small intestinal propulsion in normal mice,gastrointestinal hyper function by senna leaf mice.The models of auricular edema in mice induced by dimethyl benzene to oberve the anti-inflammatory effects of Buzhongyiqi decoction.Results Buzhongyiqi decoction can promote the intestinal motility in normal mice,varying degrees resist hyper function by senna leaf and inhibit the auricular edema.Conclusions Buzhong Yiqi decoction can adjust gastrointestinal dysfunction with dual-direction regulatio,have obvious anti-inflammatory effects.
出处
《医药论坛杂志》
2011年第22期18-19,22,共3页
Journal of Medical Forum
关键词
补中益气汤
胃肠运动
双向调节
抗炎
Buzhongyiqi decoction
Gastrointestinal peristalsis
Dual-directional regulation
Anti-inflammatory
作者简介
通讯作者：吴春明，E-mail：wu-67jp@yahoo．com．cn
