摘要
目的观察放化疗联合深部热疗治疗中晚期宫颈癌的临床疗效及不良反应。方法选取本院收治的Ⅱb-Ⅲb期宫颈癌患者70例,分为同步放化疗联合深部热疗组(试验组)和同步放化疗组(对照组),对照组进行根治性放射治疗,放疗第1天开始行化疗,顺铂40 mg静脉滴注1 d,化疗6个周期,每周重复。试验组:放化疗方法同对照组,于化疗当天行盆腹腔深部热疗(HG-2000体外高频热疗机),每次热疗60 mim,每周1次,共4次。于热疗后1 h内行放射治疗。结果两组局部肿瘤消退情况、近期疗效、肿瘤局部控制情况、1年期无瘤生存情况比较,差异有统计(P<0.05)。两组不良反应比较无统计差异。结论同步放化疗联合深部热疗可以提高患者近期疗效,且无严重的并发症,是中晚期宫颈癌治疗中的一种安全有效的模式,值得进一步研究。
Objective To observe the deep heat treatment combined radiation and chemotherapy treatment clinical curative effect of cervical cancer and adverse reaction. Methods Select 70 Ⅱb-Ⅲb period cervical cancer patients who were hospitalized in our hospital. They are divided into the chemoradiation combined deep heat treatment group （experimental group） and the chemoradiation group （control group）. The control group takes the radical radiotherapy, the 1st day of radiation therapy began to do chemotherapy, 40 mg intravenous drip 1 d, six cycles of chemotherapy, repeated every week; experimental group： the same with control group when doing Chemotherapy, the 1st day of Chemotherapy began to do the basin of chemotherapy deep heat therapy （ HG - 2000 in vitro high frequency heat therapy machine）, 60 min for each time, once a week, 4 times in total. To undergo radiation therapy within lh after heat therapy. ResuRs The difference of the compare of the local tumor resolve, short - term curative effect, tumor local control, one - year disease - free survival situation is of statistical significance （ P 〈 0.05）, while two groups of adverse reaction is of no statistical difference. Conclusion The chemoradiation combined deep heat treatment can improve the recent curative effect of patients, with no serious complications. It is a safe and effective mode for the treatment of cervical cancer, and deserves further study.
出处
《生物医学工程学进展》
CAS
2011年第4期233-235,共3页
Progress in Biomedical Engineering
关键词
同步放化疗
宫颈癌
深部热疗
临床疗效
concurrent chemotherapy, cervical carcinoma, deep heat treatment, clinical effects
作者简介
董军兰，E—mail：261123307@qq．com
