摘要
目的探讨胰头癌外科治疗的疗效。方法回顾性分析96例胰头癌患者的临床资料，其中行胰十二指肠切除术48例，扩大胰十二指切除术30例，Roux—Y胆肠吻合术18例。比较采用不同术式患者的疗效和并发症的发生率。结果胰十二指肠切除术组患者的1、2、3年生存率分别为59．2％、41．8％和13．2％，扩大胰十二指肠切除术组患者的1、2、3年生存率分别为73．2％、58．2％和24．1％，Roux-Y胆肠吻合术组患者的1、2、3年生存率分别为36．8％、15．8％和5．3％。胰十二指肠切除术组、扩大胰十二指肠切除术组和Roux—Y胆肠吻合术组患者并发症的发生率分别为29．2％、30．0％和27．8％，差异无统计学意义（P〉0．05）。结论胰十二指肠切除术是胰头癌有效的治疗方法；扩大胰十二指肠切除术提高了手术切除率，并能够通过降低局部复发率来提高胰头癌患者的生存率；Roux-Y胆肠吻合术是胰头癌重要的姑息治疗方法。
Objective To explore and evaluate the therapeutic efficacy of surgical treatment for cancer of the pancreatic head. Methods The clinical data of 96 patients with cancer of the pancreatic head admitted in our hospital from January 2002 to December 2009 were retrospectively analyzed. pancreatoduodenectomy was performed in 48 cases, extended pancreatoduodenectomy in 30 cases, and Roux- Y cholangiojejunostomy in 18 cases. Results The 1,2 and 3-year survival rates were 59.2%, 41.8% and 13.2%, respectively, in the patients treated with pancreatoduodenectomy, and 73.2%, 58.2% and 24.1% , respectively, in the patients treated with extended pancreatoduodenectomy. The 1,2 and 3-year survival rates were 36.8% , 15.8% and 5.3%, respectively, in the patients with unresectable tumor who received radiotherapy and （ or ） chemotherapy in Roux-Y cholangiojejunostomy. The postoperative morbidity was 29.2%, 30. 0% and 27.8% in the patients treated with pancreateduodenectomy, extended pancreatoduodenectomy and Roux-Y cholangiojejunostomy, respectively. Conclusions Pancreatoduodeneetomy is the most effective treatment. Extended pancreatoduodenectomy can improve the surgical resection rate, reduce the recurrence rate and improve the survival rate. Internal drainage is an important palliative measure.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
2011年第12期933-936,共4页
Chinese Journal of Oncology
关键词
胰腺肿瘤
外科手术
手术后并发症
治疗效果
预后
Pancreatic neoplasms
Surgical operation
Postoperative complications
Treatment outcome
Prognosis
作者简介
通信作者：左朝晖，Email：zuochaohui@rip．sina．com
