摘要
目的: 研究国产甲肝减毒活疫苗 (H2 株) 在小学生中的免疫效果。方法: 将431 名6～9 岁甲肝易感小学生随机分为两组。观察组接种甲肝减毒活疫苗(H2 株), 对照组接种乙肝基因工程疫苗。结果: 全部接种对象均未出现局部和全身不良反应;免疫后观察组抗-HAV 阳转率在T3 和T12时分别为85.44% 和85.64% ,而对照组则分别为12.93% 和28.32% 。结论: 两组的抗-HAV 阳转率差异有显著性, 表明国产甲肝减毒活疫苗 (H2 株)
Objective:To understand the immunogenicity of live attenuated hepatitis A vaccine(H 2 strain) in pupils.Methods:Four hundred and thirty one students susceptible to hepatitis A virus have been selected to divide into two groups randomly.Group one was inoculated with live attenuated hepatitis A vaccine(H 2 strain).Group two was inoculated with recombinant hepatitis B vaccine of gene.Results:The anti HAV positive rates of group one were 85 44% and 85 64%,respectively in T 3 and T 12 .The anti HAV positive rates of group two were 12 93% and 28 32%,respectively in T 3 and T 12 .Conclusions:Significant difference in prevalence for HAV infection was observed between two groups.Live attenuated hepatitis A vaccine(H 2 strain) was proved safe and effective,and was indeal vaccine to protect HAV infection.
出处
《现代预防医学》
CAS
1999年第4期451-452,共2页
Modern Preventive Medicine
